VanderBrink Brian A, Gitlin Jordan, Palmer Lane S
Division of Pediatric Urology, Schneider Children's Hospital of the North Shore-Long Island Jewish Health System, Long Island, New York, USA.
J Urol. 2008 Jun;179(6):2403-6; discussion 2406. doi: 10.1016/j.juro.2008.01.169. Epub 2008 Apr 23.
One measure of a successful outcome of meatoplasty for symptomatic urethral meatal stenosis has traditionally been witnessed voiding and subjective assessment of urinary stream. This evaluation is flawed by nonobjective criteria and potential differing interpretations by different clinicians. We sought to assess urinary flow better following meatoplasty using voiding uroflowmetry to measure objectively response to treatment.
We retrospectively reviewed the records of 22 boys who underwent meatoplasty for symptomatic meatal stenosis and who had uroflowmetry (flow rates, voided volumes and voiding times) performed preoperatively and postoperatively. Statistical comparison of voiding parameters was analyzed using Student's paired t test.
Mean patient age was 7 years (range 4 to 13). There were no complications and no recurrences associated with meatoplasty during a mean followup of 12 months. There was a significant increase in maximum urinary flow rates following meatoplasty (9.7 ml per second preoperatively vs 16.4 ml per second postoperatively, p = 0.001). Mean postoperative post-void residual volumes and voiding times were significantly lower than preoperative values, at 13.9 ml vs 19.3 ml (p = 0.01) and 29 seconds vs 19 seconds (p = 0.03), respectively. Voided volumes did not differ between the time intervals (157 ml preoperatively vs 147 ml postoperatively, p = 0.25). Flow patterns were abnormal in 19 of 22 patients preoperatively, and 88% of these patients had bell curve-shaped patterns following meatoplasty.
Flow rates measured by noninvasive uroflowmetry showed significant increases following meatoplasty for meatal stenosis. Uroflowmetry represents an objective method to assess outcomes following meatoplasty compared to subjective visualization of the urinary stream during voiding.
对于有症状的尿道外口狭窄行尿道口成形术成功结果的一项传统衡量指标一直是观察排尿情况及对尿流的主观评估。这种评估存在非客观标准以及不同临床医生可能有不同解读的缺陷。我们试图通过排尿尿流率测定法来更好地评估尿道口成形术后的尿流情况,以便客观地衡量治疗反应。
我们回顾性分析了22例因有症状的尿道外口狭窄而行尿道口成形术的男孩的记录,这些患儿术前和术后均进行了尿流率测定(流速、排尿量和排尿时间)。使用配对t检验对排尿参数进行统计学比较分析。
患者平均年龄为7岁(范围4至13岁)。在平均12个月的随访期间,未发生与尿道口成形术相关的并发症和复发情况。尿道口成形术后最大尿流率显著增加(术前为每秒9.7毫升,术后为每秒16.4毫升,p = 0.001)。术后平均排尿后残余尿量和排尿时间均显著低于术前值,分别为13.9毫升对19.3毫升(p = 0.01)和29秒对19秒(p = 0.03)。排尿量在不同时间间隔之间无差异(术前为157毫升,术后为147毫升,p = 0.25)。术前22例患者中有19例尿流模式异常,其中88%的患者在尿道口成形术后呈钟形曲线模式。
对于尿道外口狭窄行尿道口成形术后,通过无创尿流率测定法测得的流速显著增加。与排尿时对尿流的主观观察相比,尿流率测定是评估尿道口成形术结果的一种客观方法。