Gailbreath Katherine L, Oaks J Lindsay
Washington Animal Disease Diagnostic Laboratory, 155N Bustad Hall, Washington State University, Pullman, Washington 99164-7034, USA.
J Wildl Dis. 2008 Apr;44(2):427-33. doi: 10.7589/0090-3558-44.2.427.
A herpesviral disease of Rock Pigeons (Columba livia), called "inclusion body disease" or "inclusion body hepatitis," was first described in the 1940s. The disease involves hepatic and splenic necrosis with associated intranuclear inclusion bodies and occurs primarily in young squabs. A similar herpesviral disease occurs in falcons and owls. Serologic and restriction endonuclease digestion studies indicate that herpesviruses from pigeons, falcons, and owls are very closely related and that most reported cases of disease in falcons and owls involve prior documented or possible ingestion of pigeons. These findings led to the hypothesis that an endemic herpesvirus of pigeons may be causing disease in falcons and owls. In order to test this hypothesis, we sequenced a fragment of the herpesviral DNA polymerase gene from naturally infected owls, falcons, and pigeons with inclusion body disease collected between 1991 and 2006. Sequences from all three sources were almost identical, and we therefore propose that the usual agent of inclusion body hepatitis in owls and falcons is columbid herpesvirus 1.
一种发生于原鸽（Columba livia）的疱疹病毒性疾病，称为“包涵体病”或“包涵体肝炎”，于20世纪40年代首次被描述。该疾病涉及肝脏和脾脏坏死，并伴有核内包涵体，主要发生在幼鸽身上。一种类似的疱疹病毒性疾病发生在隼和猫头鹰身上。血清学和限制性内切酶消化研究表明，来自鸽子、隼和猫头鹰的疱疹病毒密切相关，并且大多数报道的隼和猫头鹰疾病病例都涉及先前记录的或可能摄入的鸽子。这些发现导致了这样一种假设，即鸽子的一种地方性疱疹病毒可能正在导致隼和猫头鹰患病。为了验证这一假设，我们对1991年至2006年间收集的患有包涵体病的自然感染猫头鹰、隼和鸽子的疱疹病毒DNA聚合酶基因片段进行了测序。来自所有三个来源的序列几乎相同，因此我们提出，猫头鹰和隼中包涵体肝炎的常见病原体是鸽疱疹病毒1型。
