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[慢性便秘患者结肠传输时间的不透X线标志物研究]

[Study of colonic transit time with radiopaque markers in patients with chronic constipation].

作者信息

Kolster J, de Kolter C C, Castro J, Carvajal A

机构信息

Departamento de Medicina, Universidad de Carabobo, Hospital Central, Valencia.

出版信息

G E N. 1991 Jan-Mar;45(1):14-22.

PMID:1843679
Abstract

We studied 30 young patients with idiopathic chronic constipation through the ingestion and colonic follow-up of 20 radiopaque markers, gotten from catheters of those used for intravenous lines. The number of markers were counted in each segment and total colon. Mean segmental and total colonic transit times were also calculated. There was a greater number of markers in each segment and total colon compared to 20 control subjects (p < 0.001). The mean colonic transit time was 61.4 hours (patients and 15.6 hours controls) (p < 0.001) occurring an important delay in the left colon and rectosigmoid (45.72 hours). So, in these patients there was predominantly a left colon dysfunction and the called outlet obstruction syndrome, likely related to their evacuatory habits. We do recommend this method as a valuable diagnostic tool for particularly observing the colonic progression and to offer a more rational assessment to the chronic constipated patient.

摘要

我们通过摄入并结肠追踪20个不透X线标志物,对30例特发性慢性便秘的年轻患者进行了研究,这些标志物取自静脉输液管的导管。在结肠各段及整个结肠中对标志物数量进行计数,并计算平均各段及整个结肠的转运时间。与20名对照受试者相比,患者结肠各段及整个结肠中的标志物数量更多(p < 0.001)。平均结肠转运时间为61.4小时(患者)和15.6小时(对照)(p < 0.001),在左半结肠和直肠乙状结肠处出现明显延迟(45.72小时)。因此,在这些患者中主要存在左半结肠功能障碍及所谓的出口梗阻综合征,可能与其排便习惯有关。我们确实推荐这种方法作为一种有价值的诊断工具,尤其用于观察结肠推进情况,并为慢性便秘患者提供更合理的评估。

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