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[前臂和手部软组织肉瘤。整形手术治疗]

[Soft-tissue sarcoma of the forearm and hand. Plastic surgical management].

作者信息

Müller M, Bickert B, Germann G, Sauerbier M

机构信息

Hand, Plastische und Rekonstruktive Chirurgie, BG Unfallklinik Ludwigshafen, Ludwig-Guttmann-Strasse 13, Ludwigshafen, Germany.

出版信息

Chirurg. 2008 Jul;79(7):682-8. doi: 10.1007/s00104-008-1529-3.

Abstract

Radical tumor resection (R0) is the main therapeutic goal in the treatment of sarcomas of the forearm and hand. Plastic reconstructive procedures play a key role in limb salvage by coverage of complex defects. Sophisticated reconstructive techniques are required with the forearm and hand. Twenty patients with soft-tissue sarcomas of the hand and forearm were treated in our department between January 1995 and January 2005. Eleven were male and nine were female. The average age was 48 years. The most common tumor was myxoid fibrous histiocytoma, followed by synovial cell sarcoma. Six patients received free microvascular transplantations to cover their defects. Mesh graft or primary closure was possible in three cases; one patient received a local flap and one a pedicled flap. In nine cases preserving the limb was not possible. Ten patients received radiation and four got chemotherapy (two with neoadjuvant chemotherapy). In 18 cases histologic R0 resection was possible, in two cases R1 resection. Two patients suffered from tumor recurrence after R0 resection. The average follow-up-time was 42 months. These results show the necessity of plastic surgical reconstruction of the forearm and hand as an integral component of modern sarcoma therapy. Multidisciplinary cooperation is mandatory for adequate treatment.

摘要

根治性肿瘤切除(R0)是前臂和手部肉瘤治疗的主要目标。整形重建手术通过覆盖复杂缺损在肢体挽救中发挥关键作用。前臂和手部需要复杂的重建技术。1995年1月至2005年1月期间,我科共治疗了20例手部和前臂软组织肉瘤患者。其中男性11例,女性9例。平均年龄为48岁。最常见的肿瘤是黏液样纤维组织细胞瘤,其次是滑膜肉瘤。6例患者接受了游离微血管移植以覆盖缺损。3例可行网状植皮或一期缝合;1例患者接受了局部皮瓣,1例接受了带蒂皮瓣。9例无法保肢。10例患者接受了放疗,4例接受了化疗(2例接受新辅助化疗)。18例实现了组织学R0切除,2例为R1切除。2例患者在R0切除后出现肿瘤复发。平均随访时间为42个月。这些结果表明,前臂和手部的整形手术重建作为现代肉瘤治疗不可或缺的一部分是必要的。多学科合作对于充分治疗至关重要。

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