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前臂和手部肉瘤重建的当前策略。

Current strategies for sarcoma reconstruction at the forearm and hand.

机构信息

Department of Plastic, Reconstructive and Aesthetic Surgery, Cantonal Hospital Frauenfeld, Frauenfeld, Switzerland.

出版信息

J Reconstr Microsurg. 2010 Sep;26(7):455-60. doi: 10.1055/s-0030-1254229. Epub 2010 May 10.

Abstract

Multistructural reconstructive procedures are often required to achieve a sufficient reconstruction of the forearm and/or hand after radical tumor resection. Clear margin (R0) resection is the main therapeutic goal for the treatment of sarcomas. Plastic reconstructive procedures with the possibility of microvascular transplantations play a key role in coverage of complex defects. In our department, 20 patients with soft tissue sarcomas of the hand/forearm were treated between 1995 and 2005. Eleven patients were male, nine female. The average follow-up time was 42 months. The most common tumor type was the myxoid fibrous histiocytoma in 10 cases. Six patients received a free microvascular transplantation to cover the defect after radical resection, local flaps, or primary closure was performed in five cases. Preservation was not possible in nine cases. Ten patients received radiation and four obtained chemotherapy postoperatively (two patients received neoadjuvant chemotherapy). Extremity function, the DASH questionnaire, and patient satisfaction were our examination parameters. Our results show the necessity of plastic-surgical reconstruction of the forearm and hand as an integrative component of modern sarcoma therapy. It can be concluded that plastic-surgical reconstruction of the extremity plays a key role within the multimodal concept of therapy for patients with sarcoma at the forearm and hand.

摘要

根治性肿瘤切除后,往往需要进行多结构重建手术,以充分重建前臂和/或手部。明确的边界(R0)切除是治疗肉瘤的主要治疗目标。带有微血管移植可能性的整形重建手术在覆盖复杂缺损方面起着关键作用。在我们的科室,1995 年至 2005 年间治疗了 20 例手部/前臂软组织肉瘤患者。11 例为男性,9 例为女性。平均随访时间为 42 个月。最常见的肿瘤类型是 10 例黏液样纤维组织细胞瘤。6 例患者接受游离微血管移植以覆盖根治性切除后的缺损,5 例患者行局部皮瓣或一期闭合。9 例无法保留。10 例患者接受了放疗,4 例患者术后接受了化疗(2 例患者接受了新辅助化疗)。肢体功能、DASH 问卷和患者满意度是我们的检查参数。我们的结果表明,前臂和手部的整形重建作为现代肉瘤治疗的一个组成部分是必要的。可以得出结论,对于前臂和手部肉瘤患者,整形重建在多模式治疗概念中起着关键作用。

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