Laverdiere Michele, Aggarawal Renu, Blei Francine
Department of Pediatrics, New York University Medical Center, New York, NY, USA.
Am J Perinatol. 2008 May;25(5):295-300. doi: 10.1055/s-2008-1076604. Epub 2008 Apr 24.
We attempted to identify the association of multifocal hemangiomas, specifically hepatic hemangiomatosis, in twins. We retrospectively reviewed our database of infants with hemangiomas, identifying those twins who both had hemangiomas, and we report two cases of twins with hemangiomatosis, including hepatic hemangiomas. Of 39 sets of twins in our Hemangioma Program, both twins had hemangiomas in seven twin sets. Of these seven sets, only the two reported in this article had hemangiomatosis. There were also five sets of triplets, with one set having two siblings affected by hemangiomas. We concluded that although hemangiomas in multiple gestation infants is well known, hemangiomatosis including hepatic hemangiomatosis is unusual.
我们试图确定双胞胎中多灶性血管瘤，特别是肝血管瘤病之间的关联。我们回顾性地查阅了我们的血管瘤婴儿数据库，找出了那些双方都患有血管瘤的双胞胎，并报告了两例患有血管瘤病（包括肝血管瘤）的双胞胎病例。在我们的血管瘤项目中的39对双胞胎中，有7对双胞胎双方都患有血管瘤。在这7对中，只有本文报道的2对患有血管瘤病。另外还有5组三胞胎，其中1组有两个受血管瘤影响的兄弟姐妹。我们得出结论，虽然多胎妊娠婴儿患血管瘤很常见，但包括肝血管瘤病在内的血管瘤病并不常见。
