Mustafawi A R, Hassan M E
Department of Pediatric Surgery, Alwasl Hospital, Dubai, United Arab Emirates.
Eur J Pediatr Surg. 2008 Apr;18(2):93-7. doi: 10.1055/s-2008-1038478.
Congenital duodenal obstruction (CDO) is one of the most common anomalies in newborns and infants. In 38-55% of patients, intrinsic duodenal obstruction is associated with another significant congenital anomaly. We report on a retrospective study of all children born with CDO presented to our institution over a 10-year period.
A retrospective analysis was carried out of the records of all children admitted to our center from January 1996 to December 2005 with the diagnosis of congenital duodenal obstruction. Seventy-seven patients were enrolled in the study. Age ranged from 1 day to 3 months; there were 44 males and 33 females. Weight ranged from 800 g to 4.5 kg. Five babies (6.49%) were born prematurely between 31 and 34 weeks' gestation. For the purposes of comparison, duodenal obstruction was divided into 3 groups according to the intraoperative findings. The follow-up period ranged from 6 months to 5 years. The collected data were tabulated, compared, and statistically analyzed.
Patients were divided into 3 groups: group 1 (duodenal atresia) consisted of 32 patients, group 2 (annular pancreas) consisted of 30 patients and group 3 (duodenal web) consisted of 15 patients. Twenty-five patients (32.4%) were diagnosed with pure duodenal obstruction, while 52 cases (67.5%) had other associated anomalies. Cardiac anomalies, Down syndrome, GIT anomalies and renal anomalies were the most commonly occurring associated anomalies.
Congenital duodenal obstruction repair can have a very good outcome, as our study shows. Associated congenital cardiac, GIT, and respiratory anomalies were the main cause of postoperative morbidity. Down syndrome did not influence morbidity. Mortality was unrelated to duodenal obstruction.
先天性十二指肠梗阻(CDO)是新生儿和婴儿中最常见的畸形之一。在38%至55%的患者中,先天性十二指肠梗阻与另一严重先天性畸形相关。我们报告了一项对10年间在我院出生的所有先天性十二指肠梗阻患儿的回顾性研究。
对1996年1月至2005年12月期间入住我院并诊断为先天性十二指肠梗阻的所有患儿的病历进行回顾性分析。77例患者纳入研究。年龄从1天至3个月;男44例,女33例。体重从800克至4.5千克。5例婴儿(6.49%)为孕31至34周的早产儿。为便于比较,根据术中所见将十二指肠梗阻分为3组。随访期从6个月至5年。对收集的数据进行列表、比较和统计分析。
患者分为3组:第1组(十二指肠闭锁)32例,第2组(环状胰腺)30例,第3组(十二指肠蹼)15例。25例患者(32.4%)诊断为单纯十二指肠梗阻,52例(占67.5%)有其他相关畸形。心脏畸形、唐氏综合征、胃肠道畸形和肾脏畸形是最常见的相关畸形。
正如我们的研究所显示,先天性十二指肠梗阻修复术可取得很好的效果。相关的先天性心脏、胃肠道和呼吸畸形是术后发病的主要原因。唐氏综合征不影响发病率。死亡率与十二指肠梗阻无关。