Staal J Bart, Hlobil Hynek, Köke Albère J A, Twisk Jos W R, Smid Tjabe, van Mechelen Willem
VU University Medical Center, Amsterdam, The Netherlands.
Arthritis Rheum. 2008 May 15;59(5):642-9. doi: 10.1002/art.23570.
To identify subgroups of workers absent from work due to low back pain who are more or less likely to return to work earlier as a result of a graded activity intervention, and to investigate whether this intervention is effective in reducing pain-related fears and if so, whether these reductions in pain-related fears mediate return to work.
A subgroup analysis was conducted on data from a previous randomized controlled trial of 134 Dutch airline workers, which found that a behaviorally-oriented graded activity intervention was more effective than usual care in stimulating return to work. The subgroup analyses added interaction terms to a Cox regression model that described the relationship between treatment allocation and return to work over 12 months of followup. Furthermore, we studied the effects of graded activity on pain-related fears and added variables indicating a reduction in pain-related fears to the model in order to investigate their influence on return to work.
Statistically significant interactions were found for disability, fear-avoidance beliefs about physical activity, and fear-avoidance beliefs about work. No indication was found that the reduction in pain-related fears in the graded activity group mediated more favorable return-to-work results in this group.
Workers who perceive their disability to be moderate and workers with moderate scores for fear-avoidance beliefs return to work more rapidly as a result of the graded activity intervention than workers with higher scores. The return to work of workers receiving the graded activity intervention is possibly independent from the reductions in pain-related fears caused by this intervention.
确定因腰痛而缺勤的工人亚组,这些亚组因分级活动干预而更有可能或更不可能提前复工,并调查该干预措施在减轻与疼痛相关的恐惧方面是否有效,如果有效,这些与疼痛相关的恐惧的减轻是否能促进复工。
对之前一项针对134名荷兰航空公司工人的随机对照试验数据进行亚组分析,该试验发现,以行为为导向的分级活动干预在促进复工方面比常规护理更有效。亚组分析在Cox回归模型中加入交互项,该模型描述了治疗分配与12个月随访期间复工之间的关系。此外,我们研究了分级活动对与疼痛相关的恐惧的影响,并在模型中加入表明与疼痛相关的恐惧减少的变量,以调查它们对复工的影响。
在残疾、对体育活动的恐惧回避信念和对工作的恐惧回避信念方面发现了具有统计学意义的交互作用。没有迹象表明分级活动组中与疼痛相关的恐惧的减少介导了该组更有利的复工结果。
与得分较高的工人相比,认为自己残疾程度为中度的工人以及恐惧回避信念得分中等的工人因分级活动干预而复工更快。接受分级活动干预的工人的复工可能与该干预引起的与疼痛相关的恐惧的减少无关。