Gupta Maneesh
Lancashire Care NHS Foundation Trust, Parkwood Hospital, East Park Drive, Blackpool, FY3 8PW UK.
Clin Pract Epidemiol Ment Health. 2008 Apr 25;4:11. doi: 10.1186/1745-0179-4-11.
Clozapine is the drug of choice in treatment resistant schizophrenia. It reduces hospitalizations. Patients on clozapine are often co-prescribed other psychotropics. This report looks at a sample of twenty patients on clozapine. It finds that almost two thirds were on a psychotropic along with clozapine. Eight individuals were on an antidepressant; seven on an antipsychotic and five were on co-prescribed valproate. The clinical implications are discussed and a need to look at health services involving clozapine is suggested.
氯氮平是难治性精神分裂症的首选药物。它能减少住院次数。服用氯氮平的患者通常还会同时开具其他精神药物。本报告研究了20名服用氯氮平的患者样本。发现几乎三分之二的患者在服用氯氮平的同时还服用了其他精神药物。8人服用抗抑郁药；7人服用抗精神病药，5人同时服用丙戊酸盐。文中讨论了其临床意义，并建议审视涉及氯氮平的医疗服务。
