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[大鼠尿液和粪便中氟的排泄量取决于该元素的来源及饮食中的蛋白质含量]

[Fluorine excretion in urine and feces of rats dependent on the source of this element and content of protein in the diet].

作者信息

Szewielow A

机构信息

Zakładu Badania Zywności i Przedmiotów Uzytku, Państwowego Zakładu Higieny, Warszawie.

出版信息

Rocz Panstw Zakl Hig. 1991;42(4):415-21.

PMID:1844016
Abstract

Wistar rats of both sexes were fed semisynthetic diets containing 12 or 24% of protein derived from casein or from krill meal, as well as comprising fluorine (357 mg/kg diet) either from krill meal or from sodium fluoride. After 7, 14 and 32 weeks urine and feces were collected for constructing the fluorine balance. It was found that rate fed krill meal excrete fluorine mainly in feces, and those administrated sodium fluoride--mainly in urine. A higher dietary protein level leads to enhanced fluorine excretion. Fluorine from krill meal is definitely less able to be assimilated than that from sodium fluoride. When fluorine administration is discontinued, this element is released from the organism and is excreted mainly in feces.

摘要

给雌雄Wistar大鼠喂食半合成饲料,这些饲料含有12%或24%源自酪蛋白或磷虾粉的蛋白质,并且含有来自磷虾粉或氟化钠的氟(357毫克/千克饲料)。在7周、14周和32周后,收集尿液和粪便以构建氟平衡。结果发现,喂食磷虾粉的大鼠主要通过粪便排泄氟,而喂食氟化钠的大鼠主要通过尿液排泄氟。较高的膳食蛋白质水平会导致氟排泄增加。磷虾粉中的氟肯定比氟化钠中的氟更不易被吸收。当停止给予氟时,该元素从生物体中释放出来,并且主要通过粪便排泄。

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