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介入心脏病学中的患者剂量与剂量学评估。

Patient doses and dosimetric evaluations in interventional cardiology.

作者信息

Bor Dogan, Olğar Turan, Toklu Türkay, Cağlan Ayça, Onal Elif, Padovani Renato

机构信息

Ankara University, Institute of Nuclear Science, Department of Medical Physics, Dogol, 06100 Tandoğan, Ankara, Turkey.

出版信息

Phys Med. 2009 Mar;25(1):31-42. doi: 10.1016/j.ejmp.2008.03.002. Epub 2008 Apr 25.

Abstract

Interventional cardiological examinations may be associated with excessive radiation exposures which may cause skin injuries and higher probabilities of stochastic effects. Dose-area product (DAP) and skin doses of 325 patients were measured using alternative dosimetric techniques for different cardiological examinations. Data were collected from five different systems with the involvement of 11 cardiologists. All these dosimetric information has been collected separately for each of 10 projections together with the exposure parameters of X-ray systems. Mean DAP values measured with a transparent ion chamber were 49.1 Gy cm(2), 66.8 Gy cm(2), 106.9 Gy cm(2) and 124.7 Gy cm(2), respectively, for coronary angiography (CA), percutaneous transluminal coronary angioplasty (PTCA) or stent (PT-SI), coronary angiography and/or PTCA and/or stent (CA-PT-SI), and ablation examinations. Radiochromic films, thermoluminescent dosimeters (TLD) and point measurement of air kerma (AK) were carried out for skin dose assessments. Skin doses of 23 patients measured with radiochromic films were found to be between 2 Gy and 6 Gy. Although the complexity of the procedures was the major reason for these excessive doses, considerable contributions of high X-ray output of some fluoroscopy units were also noticed. In addition to the direct measurement of DAP, alternative DAP values were also determined from the skin dose measurement techniques; exposed areas were summed on digitized radiochromic films in one technique, The product of AK reading with X-ray field size measured at the patient entrance using slow X-ray films was taken as another DAP. Good correlations were found among the DAP results and also between the entrance skin doses calculated from AK measurements and direct DAP readings (R(2)=0.91). A trigger DAP value of 130 Gy cm(2) for the 2 Gy of skin doses was derived from this relationship. Collection of dosimetric data for each projection was also investigated regarding a possible standardization of clinical techniques; in the case of coronary angiography examinations LAO 45 and RAO 30 were found as the dominant projections which may also simplify the dosimetric technique.

摘要

介入心脏病学检查可能会导致过高的辐射暴露,这可能会引起皮肤损伤以及增加随机效应的发生概率。使用替代剂量测定技术对325例患者在不同心脏病学检查中的剂量面积乘积(DAP)和皮肤剂量进行了测量。数据收集自五个不同的系统,有11位心脏病专家参与。所有这些剂量测定信息是针对10种投照方式中的每一种分别收集的,同时还包括X射线系统的曝光参数。使用透明电离室测量的冠状动脉造影(CA)、经皮腔内冠状动脉成形术(PTCA)或支架置入术(PT-SI)、冠状动脉造影和/或PTCA和/或支架置入术(CA-PT-SI)以及消融检查的平均DAP值分别为49.1 Gy cm²、66.8 Gy cm²、106.9 Gy cm²和124.7 Gy cm²。采用放射变色胶片、热释光剂量计(TLD)以及空气比释动能(AK)的点测量法进行皮肤剂量评估。用放射变色胶片测量的23例患者的皮肤剂量在2 Gy至6 Gy之间。尽管检查操作的复杂性是导致这些过高剂量的主要原因,但也注意到一些透视设备的高X射线输出也有相当大的影响。除了直接测量DAP外,还通过皮肤剂量测量技术确定了替代DAP值;一种技术是在数字化放射变色胶片上对暴露区域进行求和,另一种是将AK读数与使用慢速X射线胶片在患者入口处测量的X射线野大小的乘积作为另一个DAP。在DAP结果之间以及根据AK测量计算出的入口皮肤剂量与直接DAP读数之间发现了良好的相关性(R² = 0.91)。根据这种关系得出皮肤剂量为2 Gy时的触发DAP值为130 Gy cm²。还针对临床技术的可能标准化对每种投照方式的剂量测定数据收集情况进行了研究;在冠状动脉造影检查中,左前斜45°和右前斜30°被发现是主要的投照方式,这也可能简化剂量测定技术。

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