Jain Tarun, Missmer Stacey A
Department of Obstetrics and Gynecology, University of Illinois Medical Center, Chicago, Illinois , USA.
Fertil Steril. 2008 Sep;90(3):506-12. doi: 10.1016/j.fertnstert.2007.07.1311. Epub 2008 Apr 28.
To determine the opinions among infertility patients regarding embryonic stem cell research and to investigate the relationship between patients' choice and their demographic and socioeconomic characteristics.
Cross-sectional, self-administered survey.
University hospital-based fertility center.
PATIENT(S): A total of 1,350 consecutive women who presented for infertility care.
INTERVENTION(S): None.
MAIN OUTCOME MEASURE(S): Patient opinion regarding embryonic stem cell research, and correlations to their demographic and socioeconomic background.
RESULT(S): Of respondents with a definitive opinion, 73% felt that the use of left-over embryos for stem cell research should be allowed. After adjustment for observed predictors favoring embryonic stem cell research, we found significantly lower support for such research among patients who were younger, African American, Hispanic, less wealthy, Protestant, single, or trying to conceive for a longer duration. Those who in the past had or were currently undergoing assisted reproductive techniques were significantly more likely to approve, whereas reproductive history was not associated with the opinions about the use of spare embryos for stem cell research.
CONCLUSION(S): The majority of infertility patients studied favor use of left-over embryos for stem cell research. Several demographic and socioeconomic factors, however, are significantly associated with patient opinion.
确定不孕患者对胚胎干细胞研究的看法,并调查患者的选择与其人口统计学和社会经济特征之间的关系。
横断面、自行填写的调查。
大学附属医院的生育中心。
共有1350名连续前来寻求不孕治疗的女性。
无。
患者对胚胎干细胞研究的看法,及其与人口统计学和社会经济背景的相关性。
在有明确意见的受访者中,73%的人认为应该允许将剩余胚胎用于干细胞研究。在对支持胚胎干细胞研究的观察预测因素进行调整后,我们发现年龄较小、非裔美国人、西班牙裔、较贫困、新教徒、单身或尝试受孕时间较长的患者对这类研究的支持率明显较低。过去曾接受或正在接受辅助生殖技术的患者明显更有可能表示赞同,而生殖史与对将备用胚胎用于干细胞研究的看法无关。
大多数接受研究的不孕患者支持将剩余胚胎用于干细胞研究。然而,一些人口统计学和社会经济因素与患者的意见显著相关。