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对英国肠癌筛查计划中结肠镜检查的未来容量需求和支出进行建模。

Modelling future capacity needs and spending on colonoscopy in the English bowel cancer screening programme.

作者信息

Nnoaham K E, Lines C

机构信息

Public Health Resource Unit, Oxford Business Park South, Oxford, UK.

出版信息

Gut. 2008 Sep;57(9):1238-45. doi: 10.1136/gut.2007.146050. Epub 2008 Apr 25.

Abstract

BACKGROUND

Bowel cancer screening using faecal occult blood testing and colonoscopy is currently being rolled out across England. Guidelines recommend that people identified by colonoscopy as having intermediate- or high-risk bowel polyps be offered periodic surveillance colonoscopy because of their elevated risk of bowel cancer. We make projections of the likely year-on-year increase in volumes and spending on colonoscopy due to the screening and surveillance programmes.

METHODS

We constructed a model based on current bowel cancer screening and surveillance guidelines using screening outcome measures taken from the second round of the English bowel screening pilot. This was then used to predict colonoscopy volumes and cost for a hypothetical population.

RESULTS

For a hypothetical population of 500,000 people, with average deprivation and 66,956 subjects aged 60-74 years, the initial screening and surveillance round would be expected to detect 34 cancers at a cost of 394,157 pounds sterling. In the first 8 years, colonoscopy numbers will grow at a rate of 23 per year, most of which will be surveillance colonoscopies. Colonoscopy costs may grow by 11,808 pounds sterling yearly in the same period, representing a cost per eligible person of 2.86 pounds sterling initially, increasing by 0.13 pounds sterling every year. Sensitivity analyses suggest significant changes in these predictions if screening uptake changes by 20%.

CONCLUSION

The model has been used to make projections for five primary care trusts within the South Central Strategic Health Authority. Results from the volume and cost projections can inform service planning and resource allocation at local levels for the implementation of the current and future bowel cancer screening programme.

摘要

背景

目前,粪便潜血检测和结肠镜检查的肠癌筛查正在英格兰各地推行。指南建议,因患肠癌风险升高,被结肠镜检查确定患有中高危肠息肉的人群应接受定期监测结肠镜检查。我们对筛查和监测计划导致的结肠镜检查数量和费用可能的逐年增长进行了预测。

方法

我们基于当前的肠癌筛查和监测指南构建了一个模型,使用了取自第二轮英格兰肠癌筛查试点的筛查结果指标。然后将其用于预测假设人群的结肠镜检查数量和成本。

结果

对于一个有50万人口、平均贫困程度且有66956名60 - 74岁受试者的假设人群,初始筛查和监测轮次预计将检测出34例癌症,成本为394157英镑。在最初的8年里,结肠镜检查数量将以每年23例的速度增长,其中大部分将是监测性结肠镜检查。同期结肠镜检查成本可能每年增长11808英镑,最初每位符合条件的人的成本为2.86英镑,每年增加0.13英镑。敏感性分析表明,如果筛查接受率变化20%,这些预测会有显著变化。

结论

该模型已用于为中南部战略健康管理局内的五个初级保健信托机构进行预测。数量和成本预测结果可为地方层面实施当前及未来的肠癌筛查计划的服务规划和资源分配提供参考。

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