Rodríguez E, Gamboa M M, Fernández B
Laboratorio de Anaerobios, Facultad de Microbiología, Universidad de Costa Rica.
Rev Biol Trop. 1991 Jun;39(1):153-4.
Clinical evidence has long pointed to the existence of Clostridium tetani in Costa Rica. Thirty soil samples were studied for clostridia, and two yielded six strains of C. tetani, four of which proved to be toxigenic when mice were inoculated intraperitoneally with the culture supernates. These four isolates could be neutralized when their toxic supernates were admixed with tetanus antitoxin.
长期以来，临床证据表明哥斯达黎加存在破伤风梭菌。对30份土壤样本进行了梭菌研究，其中两份样本分离出6株破伤风梭菌，当将培养上清液腹腔注射给小鼠时，其中4株被证明具有产毒性。当将这4株分离株的毒性上清液与破伤风抗毒素混合时，其毒性可被中和。
