[日本血吸虫候选疫苗的研究现状与展望]
[Current status and prospects on candidate vaccines against Schistosoma japonicum].
作者信息
Wen Li-yong, Wu Guan-ling
机构信息
Institute of Parasitic Diseases, Zhejiang Academy of Medical Sciences, WHO Collaborating Centre for Research on Helminthiasis, Hangzhou 310013, China.
出版信息
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2007 Oct;25(5):422-5, 429.
PMID:18442002
Abstract
Great progress has been made on vaccine research for schistosomiasis, including those on immune mechanism and Schistosoma genome which have made active effect to vaccine development. This paper reviews the progress on the candidate vaccine antigens including protein vaccine, DNA vaccine and multivalent vaccine against Schistosoma japonicum.
摘要
血吸虫病疫苗研究已取得巨大进展，包括免疫机制和血吸虫基因组方面的研究，这些研究对疫苗开发产生了积极影响。本文综述了日本血吸虫候选疫苗抗原的研究进展，包括蛋白疫苗、DNA疫苗和多价疫苗。
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