Mochari Heidi, Gao Qian, Mosca Lori
New York Presbyterian Hospital Preventive Cardiology Program, New York, NY, USA.
J Am Diet Assoc. 2008 May;108(5):817-22. doi: 10.1016/j.jada.2008.02.021.
The National Cholesterol Education Program (NCEP) recommends MEDFICTS, a rapid screening instrument for dietary fat, to assess adherence to the Adult Treatment Panel (ATP) III Therapeutic Lifestyle Changes (TLC) diet (score <40 points indicates intake of <7% of energy from saturated fat, <30% of energy from total fat, and <200 mg dietary cholesterol/day). MEDFICTS has only been validated in small, select populations and its utility in diverse clinical settings is unknown.
To evaluate the ability of MEDFICTS to identify individuals who are nonadherent to a TLC diet in an ethnically diverse population that includes both English- and Spanish-speakers.
MEDFICTS was administered concurrently with the Gladys Block Food Frequency Questionnaire to participants (n=501; mean age 48+/-13.5 years; 36% nonwhite; 66% female) in the National Heart, Lung, and Blood Institute Family Intervention Trial for Heart Health (FIT Heart) at the baseline screening visit. Reliability and validity analyses were conducted overall and by sex, age, and race/ethnicity.
MEDFICTS score correlated significantly with percentage of energy from saturated fat (r=0.52, P<0.0001), percentage of energy from total fat (r=0.31, P<0.0001), and milligrams per day of dietary cholesterol (r=0.54, P<0.0001). Sensitivity of MEDFICTS to correctly identify TLC diet adherence was 85.7% and did not differ significantly by sex, age, or race/ethnicity. Specificity of MEDFICTS to correctly identify nonadherence to the TLC diet was low (56.9%) and significantly worse for women than men (48.4% vs 72.9%; P<0.0001), but did not differ significantly in older vs younger participants or among white, black, or Hispanic participants.
Our data suggest that sex-specific recalibration of MEDFICTS may improve specificity and clinical utility.
美国国家胆固醇教育计划(NCEP)推荐使用MEDFICTS(一种用于膳食脂肪的快速筛查工具)来评估对成人治疗小组(ATP)III治疗性生活方式改变(TLC)饮食的依从性(得分<40分表明饱和脂肪能量摄入<7%,总脂肪能量摄入<30%,每日膳食胆固醇摄入<200毫克)。MEDFICTS仅在小规模特定人群中得到验证,其在不同临床环境中的效用尚不清楚。
评估MEDFICTS在包括英语和西班牙语使用者的多民族人群中识别未坚持TLC饮食个体的能力。
在国家心肺血液研究所心脏健康家庭干预试验(FIT Heart)的基线筛查访视中,同时向参与者(n = 501;平均年龄48±13.5岁;36%为非白人;66%为女性)发放MEDFICTS和格拉迪斯·布洛克食物频率问卷。对总体以及按性别、年龄和种族/民族进行可靠性和有效性分析。
MEDFICTS得分与饱和脂肪能量百分比(r = 0.52,P < 0.0001)、总脂肪能量百分比(r = 0.31,P < 0.0001)以及每日膳食胆固醇毫克数(r = 0.54,P < 0.0001)显著相关。MEDFICTS正确识别TLC饮食依从性的敏感性为85.7%,在性别、年龄或种族/民族方面无显著差异。MEDFICTS正确识别未坚持TLC饮食的特异性较低(56.9%),女性显著低于男性(48.4%对72.9%;P < 0.0001),但在老年与年轻参与者之间或白人、黑人或西班牙裔参与者之间无显著差异。
我们的数据表明,对MEDFICTS进行针对性别的重新校准可能会提高其特异性和临床效用。