Baschnagel Joseph S, Coffey Scott F, Schumacher Julie A, Drobes David J, Saladin Michael E
The University at Mississippi Medical Center, Department of Psychiatry and Human Behavior, 2500 North State St. Jackson, MS 39216, USA.
University of South Florida, H. Lee Cancer Center and Research Institute, 4115 E. Fowler Ave., Tampa, FL 33617, USA.
Addict Behav. 2008 Nov;33(11):1441-1447. doi: 10.1016/j.addbeh.2008.03.004. Epub 2008 Apr 8.
Smoking rates are higher and cessation rates are lower among individuals with posttraumatic stress disorder (PTSD) compared to the general population, thus understanding the relationship between PTSD and nicotine dependence is important. In a sample of 213 participants with a crime-related trauma (109 with PTSD), the relationship between PTSD status, smoking status (smoker vs. non-smoker), substance abuse diagnosis (SUD), PTSD symptoms, and sex was assessed. SUD diagnosis was significantly related to smoking status, but PTSD symptomatology and sex were not. Among smokers (n=117), increased nicotine dependence severity was associated with being male and with increased level of PTSD avoidance symptoms. Correlations indicated that PTSD avoidance and hyperarousal symptom clusters and total PTSD symptom scores were significantly related to nicotine dependence severity in males, while PTSD symptomatology in general did not correlate with dependence severity for females. The results suggest that level of PTSD symptomatology, particularly avoidance symptoms, may be important targets for smoking cessation treatment among male smokers who have experienced a traumatic event.
与普通人群相比，创伤后应激障碍（PTSD）患者的吸烟率更高，戒烟率更低，因此了解PTSD与尼古丁依赖之间的关系很重要。在一个由213名有犯罪相关创伤经历的参与者组成的样本中（其中109人患有PTSD），评估了PTSD状态、吸烟状态（吸烟者与非吸烟者）、物质滥用诊断（SUD）、PTSD症状和性别之间的关系。SUD诊断与吸烟状态显著相关，但PTSD症状学和性别与之无关。在吸烟者（n = 117）中，尼古丁依赖严重程度增加与男性以及PTSD回避症状水平升高有关。相关性分析表明，PTSD回避和过度警觉症状群以及PTSD总症状评分与男性的尼古丁依赖严重程度显著相关，而一般来说，PTSD症状学与女性的依赖严重程度无关。结果表明，PTSD症状学水平，尤其是回避症状，可能是经历过创伤事件的男性吸烟者戒烟治疗的重要目标。
