热休克蛋白90伴侣机制。 - Suppr

The Hsp90 chaperone machinery.

作者信息

Wandinger Sebastian Karl, Richter Klaus, Buchner Johannes

机构信息

Department of Chemistry and the Center for Integrated Protein Science, Technische Universität München, 85747 Garching, Germany.

出版信息

J Biol Chem. 2008 Jul 4;283(27):18473-7. doi: 10.1074/jbc.R800007200. Epub 2008 Apr 28.

DOI:10.1074/jbc.R800007200

PMID:18442971

Abstract

摘要

相似文献

The Hsp90 chaperone machinery.

J Biol Chem. 2008 Jul 4;283(27):18473-7. doi: 10.1074/jbc.R800007200. Epub 2008 Apr 28.

A cyclophilin function in Hsp90-dependent signal transduction.

Science. 1996 Dec 6;274(5293):1713-5. doi: 10.1126/science.274.5293.1713.

Hsp90 Breaks the Deadlock of the Hsp70 Chaperone System.

Mol Cell. 2018 May 3;70(3):545-552.e9. doi: 10.1016/j.molcel.2018.03.028. Epub 2018 Apr 26.

Folding and Domain Interactions of Three Orthologs of Hsp90 Studied by Single-Molecule Force Spectroscopy.

Structure. 2018 Jan 2;26(1):96-105.e4. doi: 10.1016/j.str.2017.11.023. Epub 2017 Dec 21.

Microbial molecular chaperones.

Adv Microb Physiol. 2001;44:93-140. doi: 10.1016/s0065-2911(01)44012-4.

Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system.

EMBO J. 2003 Jul 15;22(14):3613-23. doi: 10.1093/emboj/cdg362.

The crystal structure of the carboxy-terminal dimerization domain of htpG, the Escherichia coli Hsp90, reveals a potential substrate binding site.

Structure. 2004 Jun;12(6):1087-97. doi: 10.1016/j.str.2004.03.020.

Sti1 is a novel activator of the Ssa proteins.

J Biol Chem. 2003 Jul 11;278(28):25970-6. doi: 10.1074/jbc.M301548200. Epub 2003 Apr 25.

GRP94, an ER chaperone with protein and peptide binding properties.

Semin Cell Dev Biol. 1999 Oct;10(5):495-505. doi: 10.1006/scdb.1999.0320.

Cooperation of heat shock protein 90 and p23 in aryl hydrocarbon receptor signaling.

Cell Stress Chaperones. 2004 Mar;9(1):4-20. doi: 10.1379/460.1.

引用本文的文献

HSP90's Function Under Low Temperature Stress.

Biology (Basel). 2025 Aug 1;14(8):966. doi: 10.3390/biology14080966.

Collaboration between two conserved sequence motifs drives ATPase stimulation of Hsp90 by Aha1.

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Understanding the mechanisms of resistance to azole antifungals in species.

JAC Antimicrob Resist. 2025 Jun 23;7(3):dlaf106. doi: 10.1093/jacamr/dlaf106. eCollection 2025 Jun.

The Hsp90β Isoform: An Attractive Target for Drug Development.

Med Res Rev. 2025 Sep;45(5):1452-1465. doi: 10.1002/med.22114. Epub 2025 Apr 28.

Drug Discovery for Histone Deacetylase Inhibition: Past, Present and Future of Zinc-Binding Groups.

Pharmaceuticals (Basel). 2025 Apr 16;18(4):577. doi: 10.3390/ph18040577.

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Int J Mol Sci. 2024 Aug 12;25(16):8782. doi: 10.3390/ijms25168782.

Fabrication of a low-cost benchtop optical imager for quantum dot microarray-based stress biomarker detection.

Biomed Opt Express. 2024 Jun 7;15(7):4147-4161. doi: 10.1364/BOE.527338. eCollection 2024 Jul 1.

HSP90 is part of a protein complex with the L polymerase of Rift Valley fever phlebovirus and prevents its degradation by the proteasome during the viral genome replication/transcription stage.

Front Cell Infect Microbiol. 2024 May 10;14:1331755. doi: 10.3389/fcimb.2024.1331755. eCollection 2024.

Elevated Expression of HSP72 in the Prefrontal Cortex and Hippocampus of Rats Subjected to Chronic Mild Stress and Treated with Imipramine.

Int J Mol Sci. 2023 Dec 23;25(1):243. doi: 10.3390/ijms25010243.

Protection against Aβ-induced neuronal damage by KU-32: PDHK1 inhibition as important target.

Front Aging Neurosci. 2023 Nov 14;15:1282855. doi: 10.3389/fnagi.2023.1282855. eCollection 2023.

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The Hsp90 chaperone machinery.

作者信息

Wandinger Sebastian Karl, Richter Klaus, Buchner Johannes

机构信息

Department of Chemistry and the Center for Integrated Protein Science, Technische Universität München, 85747 Garching, Germany.

出版信息

J Biol Chem. 2008 Jul 4;283(27):18473-7. doi: 10.1074/jbc.R800007200. Epub 2008 Apr 28.

DOI:10.1074/jbc.R800007200

PMID:18442971

Abstract

摘要

相似文献

The Hsp90 chaperone machinery.

J Biol Chem. 2008 Jul 4;283(27):18473-7. doi: 10.1074/jbc.R800007200. Epub 2008 Apr 28.

A cyclophilin function in Hsp90-dependent signal transduction.

Science. 1996 Dec 6;274(5293):1713-5. doi: 10.1126/science.274.5293.1713.

Hsp90 Breaks the Deadlock of the Hsp70 Chaperone System.

Mol Cell. 2018 May 3;70(3):545-552.e9. doi: 10.1016/j.molcel.2018.03.028. Epub 2018 Apr 26.

Folding and Domain Interactions of Three Orthologs of Hsp90 Studied by Single-Molecule Force Spectroscopy.

Structure. 2018 Jan 2;26(1):96-105.e4. doi: 10.1016/j.str.2017.11.023. Epub 2017 Dec 21.

Microbial molecular chaperones.

Adv Microb Physiol. 2001;44:93-140. doi: 10.1016/s0065-2911(01)44012-4.

Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system.

EMBO J. 2003 Jul 15;22(14):3613-23. doi: 10.1093/emboj/cdg362.

The crystal structure of the carboxy-terminal dimerization domain of htpG, the Escherichia coli Hsp90, reveals a potential substrate binding site.

Structure. 2004 Jun;12(6):1087-97. doi: 10.1016/j.str.2004.03.020.

Sti1 is a novel activator of the Ssa proteins.

J Biol Chem. 2003 Jul 11;278(28):25970-6. doi: 10.1074/jbc.M301548200. Epub 2003 Apr 25.

GRP94, an ER chaperone with protein and peptide binding properties.

Semin Cell Dev Biol. 1999 Oct;10(5):495-505. doi: 10.1006/scdb.1999.0320.

Cooperation of heat shock protein 90 and p23 in aryl hydrocarbon receptor signaling.

Cell Stress Chaperones. 2004 Mar;9(1):4-20. doi: 10.1379/460.1.

引用本文的文献

HSP90's Function Under Low Temperature Stress.

Biology (Basel). 2025 Aug 1;14(8):966. doi: 10.3390/biology14080966.

Collaboration between two conserved sequence motifs drives ATPase stimulation of Hsp90 by Aha1.

bioRxiv. 2025 Jun 23:2025.06.10.658861. doi: 10.1101/2025.06.10.658861.

Understanding the mechanisms of resistance to azole antifungals in species.

JAC Antimicrob Resist. 2025 Jun 23;7(3):dlaf106. doi: 10.1093/jacamr/dlaf106. eCollection 2025 Jun.

The Hsp90β Isoform: An Attractive Target for Drug Development.

Med Res Rev. 2025 Sep;45(5):1452-1465. doi: 10.1002/med.22114. Epub 2025 Apr 28.

Drug Discovery for Histone Deacetylase Inhibition: Past, Present and Future of Zinc-Binding Groups.

Pharmaceuticals (Basel). 2025 Apr 16;18(4):577. doi: 10.3390/ph18040577.

Structural Characterization of Heat Shock Protein 90β and Molecular Interactions with Geldanamycin and Ritonavir: A Computational Study.

Int J Mol Sci. 2024 Aug 12;25(16):8782. doi: 10.3390/ijms25168782.

Fabrication of a low-cost benchtop optical imager for quantum dot microarray-based stress biomarker detection.

Biomed Opt Express. 2024 Jun 7;15(7):4147-4161. doi: 10.1364/BOE.527338. eCollection 2024 Jul 1.

HSP90 is part of a protein complex with the L polymerase of Rift Valley fever phlebovirus and prevents its degradation by the proteasome during the viral genome replication/transcription stage.

Front Cell Infect Microbiol. 2024 May 10;14:1331755. doi: 10.3389/fcimb.2024.1331755. eCollection 2024.

Elevated Expression of HSP72 in the Prefrontal Cortex and Hippocampus of Rats Subjected to Chronic Mild Stress and Treated with Imipramine.

Int J Mol Sci. 2023 Dec 23;25(1):243. doi: 10.3390/ijms25010243.

Protection against Aβ-induced neuronal damage by KU-32: PDHK1 inhibition as important target.

Front Aging Neurosci. 2023 Nov 14;15:1282855. doi: 10.3389/fnagi.2023.1282855. eCollection 2023.

The Hsp90 chaperone machinery.

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The Hsp90 chaperone machinery.

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