Aplin John D, Singh Harmeet
Maternal and Fetal Health Research Group, Faculty of Medical and Human Sciences, University of Manchester, Manchester M13 0JH, UK.
Ann N Y Acad Sci. 2008 Apr;1127:116-20. doi: 10.1196/annals.1434.005.
Little is known of the genes that mediate cell interactions at implantation. A combined transcriptomics/bioinformatics protocol is described that identifies cell surface glycoproteins in endometrium with potential involvement in implantation. This is linked to an in vitro model in which functional assays of candidate gene products can be carried out.
关于介导着床时细胞相互作用的基因，我们所知甚少。本文描述了一种结合转录组学和生物信息学的方法，该方法可识别子宫内膜中可能参与着床的细胞表面糖蛋白。这与一个体外模型相关联，在该模型中可以对候选基因产物进行功能测定。
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