子宫内膜上皮细胞中的黏附分子：组织完整性与胚胎着床。
Adhesion molecules in endometrial epithelium: tissue integrity and embryo implantation.
机构信息
Maternal and Fetal Health Research Group, University of Manchester, Manchester, UK.
出版信息
J Anat. 2009 Jul;215(1):3-13. doi: 10.1111/j.1469-7580.2008.01034.x. Epub 2009 Apr 22.
Abstract
Cell adhesion in endometrial epithelium is regulated to maintain the continuity and protectiveness of the luminal covering cell layer while permitting interstitial implantation of the embryo during a restricted period of about 4 days. Many apparently normal embryos fail to implant, and epithelial-embryo adhesion remains a poorly understood phenomenon. After menstruation, epithelial regeneration occurs by epiboly from the basal residues of glands, an activity that requires migration on extracellular matrix as well as cell-cell cohesion. Here we review current knowledge of adhesion molecules in the epithelium.
摘要
子宫内膜上皮细胞的黏附受到调节，以维持腔面覆盖细胞层的连续性和保护作用，同时允许胚胎在大约 4 天的限制时间内在间质中植入。许多看似正常的胚胎无法植入，上皮-胚胎黏附仍然是一个了解甚少的现象。月经后，上皮通过从腺体的基底残留物内卷发生再生，这一活动需要在细胞外基质上迁移以及细胞-细胞黏附。在这里，我们综述了上皮细胞中黏附分子的最新知识。
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