二取代苯甲酸多齿配体的二镍配合物：脲酶活性位点的模拟物

Dinickel complexes of disubstituted benzoate polydentate ligands: mimics for the active site of urease.

作者信息

Lee Way-Zen, Tseng Huan-Sheng, Ku Meng-Yu, Kuo Ting-Shen

机构信息

Department of Chemistry, National Taiwan Normal University, 88 Sec. 4 Ting-Chow Rd., Taipei, 11677, Taiwan.

出版信息

Dalton Trans. 2008 May 21(19):2538-41. doi: 10.1039/b803094b. Epub 2008 Mar 28.

DOI:10.1039/b803094b

PMID:18443695

Abstract

Two dinickel mimics, LNi2(DMF)43 () and L'Ni2(CH3CN)43 (), for the active site of urease supported by a disubstituted benzoate polydentate ligand were synthesized and fully characterized, subsequently addition of urea afforded two urea adducts, LNi2(urea)43 () and L'Ni2(urea)43 ().

摘要

合成并全面表征了由二取代苯甲酸多齿配体支撑的两种用于脲酶活性位点的二镍模拟物，即LNi2(DMF)43 ()和L'Ni2(CH3CN)43 ()，随后加入尿素得到了两种尿素加合物，即LNi2(尿素)43 ()和L'Ni2(尿素)43 ()。