Fukushi H, Kanemoto N, Tokushima O
Central Clinical Laboratory, Tokai University Hospital, Kanagawa.
J Cardiol. 1991;21(4):1059-66.
The new electrocardiographic criteria for diagnosing left ventricular hypertrophy (LVH) were evaluated in patients with complete right bundle branch block (CRBBB) based on the relationships between left ventricular mass and multiple electrocardiographic variables obtained from 12-lead electrocardiograms. The subjects consisted of 88 patients with CRBBB, whose ages ranged from 18 to 86 years. Patients with histories of myocardial infarction, moderate to severe pericardial effusion and an undetermined axis were excluded from the study. LVH was defined as left ventricular mass (LVmass) > or = 215 g calculated from the Penn method using standard M-mode echo measurements. All electrocardiograms were interpreted by one investigator who had no knowledge of the echocardiographic results. Items calculated were the amplitude of Q, R, and S waves and their A/R, R/S, and S/A ratios, the mean frontal QRS axis, ventricular activation time in lead V5, the Morris' index, ST-T segment depression in leads V5,6, and negative U waves in leads V5,6. We selected 22 items for our criteria according to their sensitivity and specificity, and added to the 11 previously reported ones determined. LV wall thickness correlated best with R I (r = 0.57, p < 0.01), LV diastolic dimension with RV5 (r = 0.48, p < 0.01), and LV mass with R I+S III (r = 0.60, p < 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)
基于从12导联心电图获得的左心室质量与多个心电图变量之间的关系,对诊断左心室肥厚(LVH)的新心电图标准在完全性右束支传导阻滞(CRBBB)患者中进行了评估。研究对象包括88例CRBBB患者,年龄在18至86岁之间。有心肌梗死病史、中度至重度心包积液和电轴未明的患者被排除在研究之外。LVH定义为使用标准M型超声心动图测量通过Penn法计算的左心室质量(LVmass)≥215 g。所有心电图均由一名对超声心动图结果不知情的研究人员解读。计算的项目包括Q、R和S波的振幅及其A/R、R/S和S/A比值、平均额面QRS电轴、V5导联的心室激动时间、Morris指数、V5、6导联的ST-T段压低以及V5、6导联的负向U波。我们根据其敏感性和特异性选择了22项作为我们的标准,并添加到先前报道的11项已确定的标准中。左心室壁厚度与R I相关性最佳(r = 0.57,p < 0.01),左心室舒张期内径与RV5相关性最佳(r = 0.48,p < 0.01),左心室质量与R I+S III相关性最佳(r = 0.60,p < 0.01)。(摘要截断于250字)