Mardan Mohammad Akbar Ali, Mufti Tariq Saeed, Khattak Irfan Uddin, Chilkunda Nagendra, Alshayeb Abdulmonem A, Mohammad Ahmad Moussa, ur Rehman Zia
Department of Surgery, Najran General Hospital, Najran, Saudi Arabia.
J Ayub Med Coll Abbottabad. 2007 Jul-Sep;19(3):72-9.
Misdiagnosis of acute appendicitis is a common and crucial problem in general surgery. Graded compression ultrasonography is one of the new diagnostic technique that is reported to have improve the diagnostic accuracy and clinical outcome. The aim of current study is to assess the role of this diagnostic modality in the management of acute appendicitis.
This is a cohort observational study comparing the adverse outcome in two different groups of patients admitted with suspected acute appendicitis at two different hospitals in two different countries. The first group of 200 patients at Ayub Teaching Hospital Abbottabad, Pakistan, was managed without preoperative ultrasonography. In the second group of 200 patients admitted at Najran General Hospital Najran Saudi Arabia, graded compression abdominal ultrasonography was routinely performed preoperatively. Diagnostic accuracy of the protocol in each group was measured statistically and rates of negative appendicectomy and perforation were determined.
Addition of routine ultrasonography in clinical assessment for acute appendicitis decreases the sensitivity but significantly increases the specificity of the protocol thereby reducing the false positive rate translating into decreased negative appendicectomy rate. Rate of negative appendicectomy was 22.5% in group one and 4.7% in group two. Perforation rate was 15.6% in group 1 and 15% in group two.
Proper clinical assessment is the mainstay of diagnosis in acute appendicitis and addition of routine ultrasound by graded compression technique can improve the diagnostic accuracy and adverse outcome.
急性阑尾炎的误诊是普通外科常见且关键的问题。分级加压超声检查是一种新的诊断技术,据报道其提高了诊断准确性和临床效果。本研究的目的是评估这种诊断方式在急性阑尾炎治疗中的作用。
这是一项队列观察性研究,比较了在两个不同国家的两家不同医院收治的两组疑似急性阑尾炎患者的不良结局。第一组200例患者在巴基斯坦阿伯塔巴德的阿尤布教学医院接受治疗,未进行术前超声检查。第二组200例患者在沙特阿拉伯奈季兰的奈季兰综合医院收治,术前常规进行分级加压腹部超声检查。对每组方案的诊断准确性进行统计学测量,并确定阴性阑尾切除术和穿孔率。
在急性阑尾炎临床评估中增加常规超声检查会降低敏感性,但显著提高方案的特异性,从而降低假阳性率,进而降低阴性阑尾切除术率。第一组阴性阑尾切除术率为22.5%,第二组为4.7%。第一组穿孔率为15.6%,第二组为15%。
正确的临床评估是急性阑尾炎诊断的主要依据,采用分级加压技术增加常规超声检查可提高诊断准确性和改善不良结局。