加拿大魁北克省C群脑膜炎球菌结合疫苗接种后吉兰-巴雷综合征的风险。

Risk of Guillain-Barré syndrome following serogroup C meningococcal conjugate vaccine in Quebec, Canada.

作者信息

De Wals Philippe, Deceuninck Geneviève, Boucher Renée-Myriam, Ouakki Manale

机构信息

Department of Social and Preventive Medicine, Laval University, Quebec City, Canada.

出版信息

Clin Infect Dis. 2008 Apr 15;46(8):e75-7. doi: 10.1086/533469.

DOI:10.1086/533469

PMID:18444843

Abstract

To assess the risk of Guillain-Barré syndrome (GBS) following administration of meningococcal serogroup C-CRM(197) conjugate vaccine, provincial immunization records were linked with hospital discharge records, and medical charts were reviewed. In the cohort of 1.9 million individuals (age, 2 months to 20 years), observed postvaccination frequencies of GBS were not higher than expected.

摘要

为评估接种脑膜炎球菌C群-CRM(197)结合疫苗后发生格林-巴利综合征(GBS)的风险，将省级免疫记录与医院出院记录进行了关联，并查阅了病历。在190万年龄在2个月至20岁的人群队列中，观察到的接种疫苗后GBS发生率不高于预期。