Ritz Rainer, Heckl Stefan, Safavi-Abbasi Sam, Feigl Guenther C, Krischek Boris, Lüdemann Wolf, Mirzayan Javed M, Koerbel Andrei, Samii Madjid, Tatagiba Marcos, Gharabaghi Alireza
Department of Neurosurgery, Eberhard Karls University, Tübingen, Germany.
World J Surg Oncol. 2008 Apr 29;6:45. doi: 10.1186/1477-7819-6-45.
To identify preoperative and intraoperative factors and conditions that predicts the beneficial application of a high-frequency electromagnetic field (EMF) system for tumor vaporization and coagulation.
One hundred three subsequent patients with brain tumors were microsurgically treated using the EMF system in addition to the standard neurosurgical instrumentarium. A multivariate analysis was performed regarding the usefulness (ineffective/useful/very helpful/essential) of the new technology for tumor vaporization and coagulation, with respect to tumor histology and location, tissue consistency and texture, patients' age and sex.
The EMF system could be used effectively during tumor surgery in 83 cases with an essential contribution to the overall success in 14 cases. In the advanced category of effectiveness (very helpful/essential), there was a significant difference between hard and soft tissue consistency (50 of 66 cases vs. 3 of 37 cases). The coagulation function worked well (very helpful/essential) for surface (73 of 103 cases) and spot (46 of 103 cases) coagulation when vessels with a diameter of less than one millimeter were involved. The light-weight bayonet hand piece and long malleable electrodes made the system especially suited for the resection of deep-seated lesions (34 of 52 cases) compared to superficial tumors (19 of 50 cases). The EMF system was less effective than traditional electrosurgical devices in reducing soft glial tumors. Standard methods where also required for coagulation of larger vessels.
It is possible to identify factors and conditions that predict a beneficial application of high-frequency electromagnetics for tumor vaporization and coagulation. This allows focusing the use of this technology on selective indications.
确定术前和术中能够预测高频电磁场（EMF）系统在肿瘤汽化和凝固方面有益应用的因素及条件。
除标准神经外科器械外，使用EMF系统对103例后续脑肿瘤患者进行显微手术治疗。针对新技术在肿瘤汽化和凝固方面的有用性（无效/有用/非常有帮助/必不可少），就肿瘤组织学和位置、组织质地和纹理、患者年龄和性别进行多因素分析。
在83例肿瘤手术中EMF系统可有效使用，其中14例对总体成功起到了关键作用。在有效性的高级别类别（非常有帮助/必不可少）中，硬组织和软组织质地之间存在显著差异（66例中的50例与37例中的3例）。当涉及直径小于1毫米的血管时，凝固功能在表面（103例中的73例）和点状（103例中的46例）凝固方面效果良好（非常有帮助/必不可少）。与浅表肿瘤（50例中的19例）相比，轻质刺刀式手持件和可弯曲长电极使该系统特别适合切除深部病变（52例中的34例）。EMF系统在减少软质神经胶质瘤方面比传统电外科设备效果差。对于较大血管的凝固也需要标准方法。
有可能确定预测高频电磁在肿瘤汽化和凝固方面有益应用的因素及条件。这使得该技术的使用能够集中于选择性适应症。
