Okazaki Ryo
Teikyo University Chiba Medical Center, Third Department of Medicine.
Clin Calcium. 2008 May;18(5):638-43.
Both osteoporosis and atherosclerosis progress with aging. For the progression of atherosclerosis, insulin resistance, often resulted from obesity, is one of the established contributing factors. However, obesity, hence insulin resistance, act protectively for bone. Recently, chronic inflammation, associated with oxidative stress, has been proposed to be one of the missing links between atherosclerosis and osteoporosis.
骨质疏松症和动脉粥样硬化都随着年龄的增长而发展。对于动脉粥样硬化的发展，通常由肥胖导致的胰岛素抵抗是已确定的促成因素之一。然而，肥胖进而胰岛素抵抗对骨骼起到保护作用。最近，与氧化应激相关的慢性炎症被认为是动脉粥样硬化和骨质疏松症之间缺失的联系之一。
