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埃塞俄比亚北部皮肤结核的临床与流行病学研究。

Clinical and epidemiological study of cutaneous tuberculosis in Northern Ethiopia.

作者信息

Terranova Margherita, Padovese Valeska, Fornari Ugo, Morrone Aldo

机构信息

Italian Dermatological Centre, Ayder Hospital, Mekele, Ethiopia.

出版信息

Dermatology. 2008;217(1):89-93. doi: 10.1159/000128284. Epub 2008 Apr 29.

Abstract

BACKGROUND

Tuberculosis is a major public health problem in Ethiopia but cutaneous tuberculosis (CT) has not been documented.

OBJECTIVE

This study was conducted to determine its existence and its clinical pattern in Tigray, a northern region of Ethiopia.

METHODS

We report 202 cases of CT who attended the Italian Dermatological Centre in the 34-month period between January 2005 and October 2007. The diagnosis was made on a clinical, cytological and histological basis.

RESULTS

Clinically, 143 cases of scrofuloderma, 22 of lupus vulgaris, 18 of gumma, 11 of lichen scrofulosorum, 6 of tuberculosis verrucosa cutis and 2 of erythema induratum of Bazin were observed in our department. All patients were aged between 18 months and 69 years, and 49 were paediatric cases. Forty-five were HIV positive.

CONCLUSION

The number of CT cases observed in the period of 34 months indicates a high incidence of the disease in the region also in the paediatric age. CT is still underdiagnosed due to the low number of dermatologists as well as the poor life conditions of the population and the traditional belief in magic medicine. The current study may therefore provide some indication about the epidemiology of CT in Ethiopia.

摘要

背景

结核病是埃塞俄比亚的一个主要公共卫生问题,但皮肤结核(CT)尚未见相关记载。

目的

本研究旨在确定埃塞俄比亚北部提格雷地区皮肤结核的存在情况及其临床模式。

方法

我们报告了2005年1月至2007年10月这34个月期间在意大利皮肤病中心就诊的202例皮肤结核病例。诊断基于临床、细胞学和组织学依据。

结果

临床上,我们科室观察到143例瘰疬性皮肤结核、22例寻常狼疮、18例梅毒瘤、11例瘰疬性苔藓、6例疣状皮肤结核和2例巴津硬红斑。所有患者年龄在18个月至69岁之间,其中49例为儿科病例。45例为HIV阳性。

结论

在34个月期间观察到的皮肤结核病例数量表明该地区该病在儿童期也有较高发病率。由于皮肤科医生数量少、民众生活条件差以及对神奇药物的传统信仰,皮肤结核仍未得到充分诊断。因此,本研究可能为埃塞俄比亚皮肤结核的流行病学提供一些线索。

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