摩洛哥的皮肤结核病

Cutaneous tuberculosis in Morocco.

作者信息

Zouhair Kawtar, Akhdari Nadia, Nejjam Fatima, Ouazzani Tam, Lakhdar Hakima

机构信息

Dermatology Department, UHC Ibn Rochd, Casablanca, Morocco.

出版信息

Int J Infect Dis. 2007 May;11(3):209-12. doi: 10.1016/j.ijid.2006.02.009. Epub 2006 Jul 5.

DOI:10.1016/j.ijid.2006.02.009

PMID:16822685

Abstract

OBJECTIVE

To describe the salient epidemiologic, clinical, histopathologic, and bacteriologic aspects of cutaneous tuberculosis in Morocco.

METHODS

A retrospective review of all cases of cutaneous tuberculosis at our hospital from January 1981 through December 2004.

RESULTS

Two-hundred and sixteen cases of cutaneous tuberculosis were identified and included. Men and women were equally affected. The mean patient age was 29 years. Major clinical types of cutaneous tuberculosis were scrofuloderma and gumma (72%), lupus vulgaris (12%), tuberculosis verrucosa cutis (7%), tuberculids (6%), orificial tuberculosis (1%), and tuberculous chancre (1%). Systemic involvement was seen in 35%. Where performed (66%), 81% of subjects had positive Mantoux skin tests. Lesion biopsy for histopathologic study was performed in 81% of patients and showed classical tuberculous findings in 57%. Mycobacterium tuberculosis was isolated in culture from 9% of patients.

CONCLUSION

Cutaneous tuberculosis is still a common disease in Morocco, and scrofuloderma and gumma are the most common clinical presentations.

摘要

目的

描述摩洛哥皮肤结核显著的流行病学、临床、组织病理学及细菌学特征。

方法

对我院1981年1月至2004年12月期间所有皮肤结核病例进行回顾性分析。

结果

共确定并纳入216例皮肤结核病例。男女受累情况相同。患者平均年龄为29岁。皮肤结核的主要临床类型为瘰疬性皮肤结核和梅毒瘤（72%）、寻常狼疮（12%）、疣状皮肤结核（7%）、结核疹（6%）、腔口结核（1%）及结核性溃疡（1%）。35%的患者出现全身受累。在进行检测的患者中（66%），81%的受试者结核菌素皮肤试验呈阳性。81%的患者进行了病变活检以进行组织病理学研究，其中57%显示出典型的结核表现。9%的患者培养分离出结核分枝杆菌。