Unexpected failure rates for modular assembly of engineered zinc fingers.
作者信息
Ramirez Cherie L, Foley Jonathan E, Wright David A, Müller-Lerch Felix, Rahman Shamim H, Cornu Tatjana I, Winfrey Ronnie J, Sander Jeffry D, Fu Fengli, Townsend Jeffrey A, Cathomen Toni, Voytas Daniel F, Joung J Keith
出版信息
Nat Methods. 2008 May;5(5):374-5. doi: 10.1038/nmeth0508-374.
Abstract
摘要
相似文献
1
Unexpected failure rates for modular assembly of engineered zinc fingers.工程化锌指蛋白模块化组装的意外失败率。
Nat Methods. 2008 May;5(5):374-5. doi: 10.1038/nmeth0508-374.
2
Genome editing with modularly assembled zinc-finger nucleases.使用模块化组装锌指核酸酶进行基因组编辑。
Nat Methods. 2010 Feb;7(2):91; author reply 91-2. doi: 10.1038/nmeth0210-91a.
3
Genome editing goes global.基因组编辑走向全球。
Biotechniques. 2011 Dec;51(6):371-3. doi: 10.2144/000113775.
4
Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly.通过模块化组装构建锌指核酸酶的标准化试剂和方案。
Nat Protoc. 2006;1(3):1637-52. doi: 10.1038/nprot.2006.259.
5
Engineering designer nucleases with customized cleavage specificities.设计具有定制切割特异性的工程化核酸酶。
Curr Protoc Mol Biol. 2011 Oct;Chapter 12:Unit12.13. doi: 10.1002/0471142727.mb1213s96.
6
Beyond TALENs.超越转录激活样效应因子核酸酶（TALENs）
Science. 2012 Dec 14;338(6113):1411. doi: 10.1126/science.338.6113.1411.
7
The tale of the TALEs.转录激活样效应因子的故事。
Science. 2012 Dec 14;338(6113):1408-11. doi: 10.1126/science.338.6113.1408.
8
Site-specific DNA excision via engineered zinc finger nucleases.通过工程化锌指核酸酶进行位点特异性DNA切除。
Trends Biotechnol. 2010 Sep;28(9):445-6. doi: 10.1016/j.tibtech.2010.06.004. Epub 2010 Jul 10.
9
Zinc-finger nucleases-based genome engineering to generate isogenic human cell lines.基于锌指核酸酶的基因组工程技术用于构建等基因人类细胞系。
Methods Mol Biol. 2012;813:145-56. doi: 10.1007/978-1-61779-412-4_8.
10
Genome engineering: the next genomic revolution.基因组工程：下一场基因组革命。
Nat Methods. 2014 Oct;11(10):1009-11. doi: 10.1038/nmeth.3113.
引用本文的文献
1
Genome editing strategies for targeted correction of β-globin mutation in sickle cell disease: From bench to bedside.镰状细胞病中β-珠蛋白突变靶向校正的基因组编辑策略：从实验台到病床边
Mol Ther. 2025 May 7;33(5):2154-2171. doi: 10.1016/j.ymthe.2025.03.047. Epub 2025 Mar 30.
2
Synthetic gene circuits in plants: recent advances and challenges.植物中的合成基因回路：最新进展与挑战
Quant Plant Biol. 2025 Feb 27;6:e6. doi: 10.1017/qpb.2025.3. eCollection 2025.
3
Looking to the Future of Viral Vectors in Ocular Gene Therapy: Clinical Review.展望眼部基因治疗中病毒载体的未来：临床综述
Biomedicines. 2025 Feb 5;13(2):365. doi: 10.3390/biomedicines13020365.
4
Advancements in genome editing tools for genetic studies and crop improvement.用于基因研究和作物改良的基因组编辑工具的进展。
Front Plant Sci. 2025 Feb 3;15:1370675. doi: 10.3389/fpls.2024.1370675. eCollection 2024.
5
Advancing crop disease resistance through genome editing: a promising approach for enhancing agricultural production.通过基因组编辑提升作物抗病性：一种提高农业产量的有前景的方法。
Front Genome Ed. 2024 Jun 26;6:1399051. doi: 10.3389/fgeed.2024.1399051. eCollection 2024.
6
Engineering of Zinc Finger Nucleases Through Structural Modeling Improves Genome Editing Efficiency in Cells.通过结构建模工程化锌指核酸酶可提高细胞中的基因组编辑效率。
Adv Sci (Weinh). 2024 Jun;11(23):e2310255. doi: 10.1002/advs.202310255. Epub 2024 Apr 10.
7
Precise genome-editing in human diseases: mechanisms, strategies and applications.人类疾病中的精确基因组编辑：机制、策略和应用。
Signal Transduct Target Ther. 2024 Feb 26;9(1):47. doi: 10.1038/s41392-024-01750-2.
8
Gene Editing in Hematopoietic Stem Cells.造血干细胞中的基因编辑。
Adv Exp Med Biol. 2023;1442:177-199. doi: 10.1007/978-981-99-7471-9_11.
9
Site-specific genome editing in treatment of inherited diseases: possibility, progress, and perspectives.位点特异性基因组编辑在遗传性疾病治疗中的应用：可能性、进展与展望
Med Rev (2021). 2022 Nov 11;2(5):471-500. doi: 10.1515/mr-2022-0029. eCollection 2022 Oct.
10
Corneal gene therapy: Structural and mechanistic understanding.角膜基因治疗：结构与机制的理解。
Ocul Surf. 2023 Jul;29:279-297. doi: 10.1016/j.jtos.2023.05.007. Epub 2023 May 25.
本文引用的文献
1
Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly.通过模块化组装构建锌指核酸酶的标准化试剂和方案。
Nat Protoc. 2006;1(3):1637-52. doi: 10.1038/nprot.2006.259.
2
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases.锌指工具：用于转录因子和核酸酶的定制DNA结合结构域。
Nucleic Acids Res. 2006 Jul 1;34(Web Server issue):W516-23. doi: 10.1093/nar/gkl209.
3
Gene targeting using zinc finger nucleases.使用锌指核酸酶进行基因靶向。
Nat Biotechnol. 2005 Aug;23(8):967-73. doi: 10.1038/nbt1125.
4
Human zinc fingers as building blocks in the construction of artificial transcription factors.作为构建人工转录因子组件的人类锌指蛋白。
Nat Biotechnol. 2003 Mar;21(3):275-80. doi: 10.1038/nbt796. Epub 2003 Feb 18.
5
Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins.新型多聚锌指DNA结合蛋白构建的模块化策略评估
Biochemistry. 2003 Feb 25;42(7):2137-48. doi: 10.1021/bi026806o.
6
Validated zinc finger protein designs for all 16 GNN DNA triplet targets.针对所有16个GNN DNA三联体靶标的经过验证的锌指蛋白设计。
J Biol Chem. 2002 Feb 8;277(6):3850-6. doi: 10.1074/jbc.M110669200. Epub 2001 Nov 28.
Zotero 插件