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[抗心磷脂抗体与中枢神经系统原发性抗磷脂综合征:10例临床病例报告]

[Anticardiolipin antibodies and primary antiphospholipid syndrome of the central nervous system: report of 10 clinical cases].

作者信息

Córdova J L, Neira O, Abumohor P, Palma S, Vergara F, Guzmán L

机构信息

Servicio de Neurología, Hospital Dr Sótero del Río, Santiago, Chile.

出版信息

Rev Med Chil. 1991 Jul;119(7):765-71.

PMID:1844751
Abstract

An association between anti-phospholipid antibodies and different disorders of the central nervous system has been described recently. We used an ELISA technique and detected anti-cardiolipin antibodies of the IgG or IgM variety in a series of 10 patients: 4 had occlusive stroke, 2 brain hemorrhage, 2 chorea, 1 a Sneddon syndrome and 1 vascular cephalea. The diagnosis of primary anti-phospholipid syndrome was suggested after ruling out systemic lupus in all patients.

摘要

最近已描述了抗磷脂抗体与中枢神经系统不同疾病之间的关联。我们使用酶联免疫吸附测定(ELISA)技术,在一组10例患者中检测到了IgG或IgM型抗心磷脂抗体:4例患有闭塞性中风,2例脑出血,2例舞蹈病,1例斯内登综合征和1例血管性头痛。在排除所有患者的系统性红斑狼疮后,提示诊断为原发性抗磷脂综合征。

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