Pee Yong Hun, Park Jong Dae, Choi Young-Geun, Lee Sang-Ho
Department of Neurosurgery, Wooridul Spine Hospital, Seoul, Korea.
J Neurosurg Spine. 2008 May;8(5):405-12. doi: 10.3171/SPI/2008/8/5/405.
An anterior approach for debridement and fusion with autologous bone graft has been recommended as the gold standard for surgical treatment of pyogenic spondylodiscitis. The use of anterior foreign body implants at the site of active infection is still a challenging procedure for spine surgeons. Several authors have recently introduced anterior grafting with titanium mesh cages instead of autologous bone strut in the treatment of spondylodiscitis. The authors present their experience of anterior fusion with 3 types of cages followed by posterior pedicle screw fixation. They also compare their results with the use of autologous iliac bone strut.
The authors retrospectively reviewed the cases of 60 patients with pyogenic spondylodiscitis treated by anterior debridement between January 2003 and April 2005. Fusion using either cages or iliac bone struts was performed during the same course of anesthesia followed by posterior fixation. Twenty-three patients underwent fusion with autologous iliac bone strut, and 37 patients underwent fusion with 1 of the 3 types of cages.
The infections resolved in all patients, as noted by normalization of their erythrocyte sedimentation rates and C-reactive protein levels. Patients in both groups were evaluated in terms of their preoperative and postoperative clinical and imaging findings.
Single-stage anterior debridement and cage fusion followed by posterior pedicle screw fixation can be effective in the treatment of pyogenic spondylodiscitis. There was no difference in clinical and imaging outcomes between the strut group and cage group except for the subsidence rate. The subsidence rate was higher in the strut group than in the cage group. The duration until subsidence was also shorter in the strut group than in the cage group.
前路清创并自体骨移植融合术已被推荐为化脓性脊椎间盘炎外科治疗的金标准。在活跃感染部位使用前路异体植入物对脊柱外科医生来说仍是一项具有挑战性的手术。最近,几位作者介绍了在治疗脊椎间盘炎时使用钛网笼进行前路植骨而非自体骨支柱的方法。作者介绍了他们使用3种不同类型的椎间融合器进行前路融合并随后行后路椎弓根螺钉固定的经验。他们还将结果与使用自体髂骨支柱的情况进行了比较。
作者回顾性分析了2003年1月至2005年4月间60例接受前路清创治疗的化脓性脊椎间盘炎患者的病例。在同一麻醉过程中使用椎间融合器或髂骨支柱进行融合,随后进行后路固定。23例患者采用自体髂骨支柱融合,37例患者采用3种椎间融合器中的1种进行融合。
所有患者感染均得到解决,红细胞沉降率和C反应蛋白水平恢复正常。根据术前和术后的临床及影像学表现对两组患者进行评估。
一期前路清创、椎间融合器融合并后路椎弓根螺钉固定可有效治疗化脓性脊椎间盘炎。除下沉率外,支柱组和椎间融合器组的临床及影像学结果无差异。支柱组的下沉率高于椎间融合器组。支柱组下沉发生的时间也比椎间融合器组短。