Jagannathan Jay, Shaffrey Christopher I, Oskouian Rod J, Dumont Aaron S, Herrold Christian, Sansur Charles A, Jane John A
Department of Neurological Surgery, University of Virginia Health System, Box 800212, Charlottesville, Virginia 22908, USA.
J Neurosurg Spine. 2008 May;8(5):420-8. doi: 10.3171/SPI/2008/8/5/420.
Although the clinical outcomes following anterior cervical discectomy and fusion (ACDF) surgery are generally good, 2 major complications are graft migration and nonunion. These complications have led some to advocate rigid internal fixation and/or cervical immobilization postoperatively. This paper examines a single-surgeon experience with single-level ACDF without use of plates or hard collars in patients with degenerative spondylosis in whom allograft was used as the fusion material.
The authors conducted a retrospective review of a prospective database of (Cloward-type) ACDF operations performed by the senior author (J.A.J.) between July 1996 and June 2005. Radiographic follow-up included static and flexion/extension radiographs obtained to assess fusion, focal and segmental kyphosis, and change in disc space height. At most recent follow-up, the patients' condition was evaluated by an independent physician examiner. The Odom criteria and Neck Disability Index (NDI) were used to assess outcome.
One hundred seventy patients underwent single-level ACDF for degenerative pathology during the study period. Their most common presenting symptoms were pain, weakness, and radiculopathy; 88% of patients noted >or= 2 neurological complaints. The mean hospital stay was 1.76 days (range 0-36 days), and 3 patients (2%) had major immediate postoperative complications requiring reoperation. The mean duration of follow-up was 22 months (range 12-124 months). Radiographic evidence of fusion was present in 160 patients (94%). Seven patients (4%) showed radiographic evidence of pseudarthrosis, and graft migration was seen in 3 patients (2%). All patients had increases in focal kyphosis at the operated level on postoperative radiographs (mean -7.4 degrees ), although segmental alignment was preserved in 133 patients (78%). Mean change in disc space height was 36.5% (range 28-53%). At most recent clinical follow-up, 122 patients (72%) had no complaints referable to cervical disease and were able to carry out their activities of daily living without impairment. The mean postoperative NDI score was 3.2 (median 3, range 0-31).
Single-level ACDF without intraoperative plate placement or the use of a postoperative collar is an effective treatment for cervical spondylosis. Although there is evidence of focal kyphosis and loss of disc space height, radiographic evidence of fusion is comparable to that attained with plate fixation, and the rate of clinical improvement is high.
尽管颈椎前路椎间盘切除融合术(ACDF)后的临床效果总体良好,但有两大并发症,即移植物移位和骨不连。这些并发症促使一些人主张术后采用坚强内固定和/或颈部制动。本文探讨了一位外科医生在治疗退变性脊椎病患者时,采用单节段ACDF且不使用钢板或硬颈托,使用同种异体骨作为融合材料的经验。
作者对资深作者(J.A.J.)在1996年7月至2005年6月期间进行的(Cloward型)ACDF手术的前瞻性数据库进行了回顾性研究。影像学随访包括获取静态和屈伸位X线片,以评估融合情况、局部和节段性后凸以及椎间隙高度变化。在最近一次随访时,由独立的医生检查者评估患者的病情。采用奥多姆标准和颈部残疾指数(NDI)评估治疗效果。
在研究期间,170例患者因退变性病变接受了单节段ACDF手术。他们最常见的症状是疼痛、无力和神经根病;88%的患者有≥2项神经方面的主诉。平均住院时间为1.76天(范围0 - 36天),3例患者(2%)出现严重的术后即刻并发症,需要再次手术。平均随访时间为22个月(范围12 - 124个月)。160例患者(94%)有融合的影像学证据。7例患者(4%)有假关节形成的影像学证据,3例患者(2%)出现移植物移位。所有患者术后X线片显示手术节段局部后凸均有增加(平均 -7.4度),不过133例患者(78%)节段对线保持良好。椎间隙高度平均变化为36.5%(范围28 - 53%)。在最近一次临床随访时,122例患者(72%)无颈椎病相关主诉,能够无障碍地进行日常生活活动。术后NDI评分平均为3.2(中位数3,范围0 - 31)。
术中不放置钢板或术后不使用颈托的单节段ACDF是治疗颈椎病的一种有效方法。尽管有局部后凸和椎间隙高度丢失的证据,但融合的影像学证据与钢板固定相当,且临床改善率较高。