Piñeiro Pérez R, Mellado Peña M J, Méndez Echevarría A, Cilleruelo Ortega M J, García Hortelano M, Villota Arrieta J, Martín Fontelos P
Servicio de Pediatría, Hospital Carlos III, Madrid, España.
An Pediatr (Barc). 2008 May;68(5):490-5. doi: 10.1157/13120048.
A world increase in multidrug-resistant tuberculosis (MDR-TB) has been reported over the last few years. A larger number of diagnoses are being seen in Spain, due to the increase of immigration from high endemic TB countries. Articles published on this are anecdotal in children, and there is no clear directives for treatment of MDR-TB, or latent tuberculosis infection (ITBL) or on prophylaxis after exposure to active pulmonary MDR-TB. We present the initial management and progression of nine children after close contact exposure to an Ecuadorian woman diagnosed with active pulmonary TB, resistant to Isoniazid, Rifampicin and Pyrazinamide.
在过去几年中，已有报道称全球耐多药结核病（MDR-TB）有所增加。由于来自结核病高流行国家的移民增多，西班牙出现了更多此类诊断病例。关于这方面在儿童中的报道多为个案，对于耐多药结核病、潜伏性结核感染（LTBI）的治疗或接触活动性肺结核耐多药病例后的预防，尚无明确的指导方针。我们介绍了9名儿童在密切接触一名被诊断为活动性肺结核、对异烟肼、利福平及吡嗪酰胺耐药的厄瓜多尔女性后的初始处理及病情进展情况。
