Thapa Rajoo, Mukherjee Swapan
Department of Pediatrics and Pediatric Neurology Unit, The Institute of Child Health, Kolkata, West Bengal, India.
J Child Neurol. 2008 May;23(5):580-1. doi: 10.1177/0883073807309774.
Pseudotumor cerebri is a clinical condition marked by papilledema, normal cerebrospinal fluid composition, normal or small ventricles on radiography, and absence of an intracranial mass. In this condition, headache, tinnitus, dizziness, blurred vision, and diplopia are frequently observed. The cause is often unknown but can occur with certain drug ingestions or systemic inflammatory and metabolic diseases. The treatment is primarily focused on the correction of the underlying cause with measures to reduce the raised intracranial pressure. The most important complication is optic atrophy, which results in visual loss. The sixth cranial nerve is most commonly affected. The involvement of the third cranial nerve is distinctly unusual. The present report describes a unique case of bilateral oculomotor palsy with sparing of the papillary fibers. It resolved promptly on administration of acetazolamide.
假性脑瘤是一种临床病症,其特征为视乳头水肿、脑脊液成分正常、影像学检查显示脑室正常或较小,且无颅内占位。在此病症中,常出现头痛、耳鸣、头晕、视力模糊和复视。病因通常不明,但可与某些药物摄入或全身性炎症及代谢性疾病相关。治疗主要侧重于纠正潜在病因,并采取措施降低升高的颅内压。最重要的并发症是视神经萎缩,可导致视力丧失。第六对脑神经最常受累。第三对脑神经受累则极为罕见。本报告描述了一例独特的双侧动眼神经麻痹病例,乳头纤维未受累。使用乙酰唑胺后症状迅速缓解。