Ernesto S, Marduel Y, Freymond N, Pacheco Y, Devouassoux G
Service de Pneumologie, Centre Hospitalier Lyon Sud, HCL, Lyon, France.
Rev Mal Respir. 2008 Mar;25(3):328-32. doi: 10.1016/s0761-8425(08)71553-5.
Twenty five per cent of thermal injuries are associated with secondary respiratory events linked to several mechanisms. In the acute phase of the accident oedema of the airways, the fume inhalation syndrome and ARDS are the most common causes responsible for death in 60% of cases. Late respiratory complications are little known and neglected. They comprise obstructive ventilatory defects due to the inhalation syndrome and restrictive defects secondary to ARDS or to dermal injury.
We report the case of a female patient, extensively burnt 2 years previously, admitted to hospital with severe acute respiratory failure complicating COPD. The presence of both restrictive and obstructive defects led to the suggestion of alternative underlying mechanisms such as the pulmonary consequences of ARDS and extensive dermal scars. The latter were responsible for an armour like thickening of the skin of the thorax compatible with the restrictive defect.
These functional abnormalities and the potential severity of acute respiratory failure are indications for regular pulmonary follow-up of patients with severe circumferential scarring of the thorax who are at high risk for respiratory complications.
25%的热烧伤与继发于多种机制的呼吸事件相关。在事故急性期,气道水肿、烟雾吸入综合征和急性呼吸窘迫综合征(ARDS)是导致60%病例死亡的最常见原因。晚期呼吸并发症鲜为人知且被忽视。它们包括因吸入综合征导致的阻塞性通气缺陷以及继发于ARDS或皮肤损伤的限制性缺陷。
我们报告一例女性患者,两年前曾大面积烧伤,因慢性阻塞性肺疾病(COPD)并发严重急性呼吸衰竭入院。同时存在限制性和阻塞性缺陷提示了其他潜在机制,如ARDS的肺部后果和广泛的皮肤瘢痕。后者导致胸部皮肤出现铠甲样增厚,符合限制性缺陷。
这些功能异常以及急性呼吸衰竭的潜在严重性表明,对于胸部有严重环形瘢痕且有呼吸并发症高风险的患者,应定期进行肺部随访。