Núñez E, Varela S, Cervilla K, Shalper J
Servicio de Pediatría, Hospital Higueras, Talcahuano.
Rev Chil Pediatr. 1991 May-Jun;62(3):186-8.
A term female infant of hydropic aspect was born from an A II Rh positive mother who had not submitted herself to prenatal medical controls. From delivery the newborn showed evidence of hydrops, tendency to bleed from needle puncture sites and poor respiratory effort, there fore it was necessary to support her with mechanical ventilation, but she died three hours after birth. Autopsy findings included proliferation of immature white blood cells of myeloid type with reduction of red blood cell precursors and megakaryocytes at the bone marrow. The same immature cell forms also infiltrated liver, spleen, lungs and adrenal glands. Leukemia is seldom seen in the neonatal period an it has been described in only rare occasions associated to non-immunological fetal hydrops.
一名全身水肿的足月女婴，其母亲为A II Rh阳性，未进行产前医学检查。自分娩起，新生儿就表现出水肿迹象、针刺部位出血倾向以及呼吸功能不佳，因此有必要对其进行机械通气支持，但她在出生三小时后死亡。尸检结果包括骨髓中髓样未成熟白细胞增殖，红细胞前体和巨核细胞减少。同样的未成熟细胞形式也浸润了肝脏、脾脏、肺和肾上腺。新生儿期很少见到白血病，仅在极少数与非免疫性胎儿水肿相关的情况下有过描述。
