Achiam Michael Patrick, Løgager Vibeke Berg, Chabanova Elizaveta, Eegholm Bodil, Thomsen Henrik Segelcke, Rosenberg Jacob
Department of Diagnostic Radiology, Copenhagen University Hospital Herlev, Herlev, Denmark.
Abdom Imaging. 2009 Jul;34(4):483-90. doi: 10.1007/s00261-008-9402-x.
MR colonography (MRC) is a non-invasive method of examining the colon, but it is still only used in a few specialized centers on a daily basis. The purpose of this study was to evaluate the performance of MRC with improved fecal tagging vs. conventional colonoscopy (CC).
Between March 2006 and February 2007, consecutive patients who received first-time referrals to CC were asked to participate in the study. Two days prior to MRC, a new contrast mixture (barium/ferumoxsil) was ingested together with four meals each day. Standard bowel cleansing was performed before CC. MRC was evaluated by two blinded observers. MRC results were compared with CC.
A total of 56 patients were included. The per-polyp sensitivity was 85.7% for polyps 6-10 mm and 81.3% for polyps >10 mm. The per-patient sensitivity/specificity was 100%/80% for polyps >6 mm and 100%/91.4% for polyps >10 mm.
MRC showed acceptable per-patient sensitivities, but the per-polyp sensitivities are still compromised by the fecal tagging. MRC may be implemented, but at the present time MRC with fecal tagging is not ready for widespread use, although it remains a very promising diagnostic tool.
磁共振结肠成像（MRC）是一种检查结肠的非侵入性方法，但目前仍仅在少数专业中心每日使用。本研究的目的是评估改进粪便标记的MRC与传统结肠镜检查（CC）的性能。
在2006年3月至2007年2月期间，连续首次转诊至CC的患者被要求参与研究。在MRC检查前两天，每天随四餐摄入一种新的造影剂混合物（钡/铁硅）。在CC检查前进行标准肠道清洁。由两名盲法观察者评估MRC。将MRC结果与CC结果进行比较。
共纳入56例患者。对于6 - 10毫米的息肉，每息肉敏感性为85.7%，对于大于10毫米的息肉，每息肉敏感性为81.3%。对于大于6毫米的息肉，每患者敏感性/特异性为100%/80%，对于大于10毫米的息肉，每患者敏感性/特异性为100%/91.4%。
MRC显示出可接受的每患者敏感性，但每息肉敏感性仍受粪便标记的影响。MRC可以实施，但目前带有粪便标记的MRC尚未准备好广泛应用，尽管它仍然是一种非常有前景的诊断工具。
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