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脑肿瘤清醒开颅手术的历史及其在亚洲的传播。

The history of awake craniotomy for brain tumor and its spread into Asia.

作者信息

July Julius, Manninen Pirjo, Lai Jacob, Yao Zhenhai, Bernstein Mark

机构信息

Division of Neurosurgery, University Health Network, Toronto Western Hospital, Toronto, Ontario, Canada M5T 2S8.

出版信息

Surg Neurol. 2009 May;71(5):621-4; discussion 624-5. doi: 10.1016/j.surneu.2007.12.022. Epub 2008 May 2.

Abstract

In ancient times, awake craniotomy was used for trepanation to treat seizures and remove a variety of morbid conditions or even to permit the escape of evil air. In modern times, this technique was initially used for removal of epileptic foci with simultaneous application of brain mapping with electrical current. Further developments brought this technique into use for resection of tumors involving functional cortex. Recently, awake craniotomy has been described as an approach for removal of supratentorial tumors nonselectively, regardless of the involvement of eloquent cortex. It has been used in North America since the 1980s, then Europe, and recently has spread into Asia. Its spread to Asia could have significant impact based on the large population of patients and the low resource utilization associated with awake craniotomy.

摘要

在古代,清醒开颅术被用于颅骨钻孔,以治疗癫痫发作、消除各种病症,甚至是为了让邪气逸出。在现代,这项技术最初用于切除癫痫病灶,同时应用电流进行脑图谱绘制。进一步的发展使该技术用于切除累及功能区皮质的肿瘤。最近,清醒开颅术被描述为一种非选择性切除幕上肿瘤的方法,无论明确的皮质是否受累。自20世纪80年代以来,它已在北美使用,然后在欧洲使用,最近已传播到亚洲。鉴于患者数量众多以及清醒开颅术相关的资源利用率较低,它在亚洲的传播可能会产生重大影响。

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