Kurnutala Lakshmi N, Chauhan Vikas, Smith Richard S, Tucci Michelle
Anesthesiology, University of Mississippi Medical Center, Jackson, USA.
Cureus. 2025 Mar 28;17(3):e81344. doi: 10.7759/cureus.81344. eCollection 2025 Mar.
Awake craniotomies (AC) are an increasingly popular surgical technique used in medical institutions worldwide. This rise in adoption is largely due to improved patient outcomes and satisfaction. This procedure allows for real-time monitoring of neurological functions, which helps surgeons preserve critical cognitive, language, and motor abilities. As a result, patients tend to retain neurological functions closer to their baseline levels, highlighting the technique's advantages in modern neurosurgery. Neuromonitoring and brain mapping allow surgeons to perform resections more precisely in delicate anatomical areas. We developed and implemented a protocol for awake craniotomy procedures at the University of Mississippi Medical Center a few years ago. The purpose of this study was to assess and analyze the data between anesthetic management of awake craniotomy and traditional craniotomy (TC). We compared patient characteristics, anesthetic management, surgical duration, complications, opioid requirements, and length of hospital stay (LOS). Our results indicated a statistically significant reduction in the opioid requirement for patients in the awake craniotomy group with no difference in the overall length of stay.
清醒开颅手术（AC）是一种在全球医疗机构中越来越受欢迎的外科技术。其应用的增加主要归功于患者预后的改善和满意度的提高。该手术允许对神经功能进行实时监测，这有助于外科医生保留关键的认知、语言和运动能力。因此，患者往往能将神经功能维持在更接近其基线水平，凸显了该技术在现代神经外科中的优势。神经监测和脑图谱使外科医生能够在精细的解剖区域更精确地进行切除。几年前，我们在密西西比大学医学中心制定并实施了一项清醒开颅手术方案。本研究的目的是评估和分析清醒开颅手术与传统开颅手术（TC）麻醉管理之间的数据。我们比较了患者特征、麻醉管理、手术时长、并发症、阿片类药物需求量和住院时间（LOS）。我们的结果表明，清醒开颅手术组患者的阿片类药物需求量有统计学意义的显著降低，而总体住院时间没有差异。
