Samano M N, Waisberg D R, Villiger L E O, Pêgo-Fernandes P M, Jatene F B
Heart Institute (InCor) do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Transplant Proc. 2008 Apr;40(3):872-4. doi: 10.1016/j.transproceed.2008.02.057.
Suppurative lung diseases, such as cystic fibrosis and bronchiectasis, when diffuse and associated with important functional loss, can be treated with bilateral lung transplantation with good results. These diseases are frequently associated with previous lung resections presenting an asymmetric thorax, thus making lung extraction difficult and generating disproportion between the graft and the pleural cavity. To treat this condition, pneumonectomy and single lung transplantation is a feasible option; however, there are associated comorbidities and an invariable need for extracorporeal circulation. Described herein are 2 patients with an asymmetric thorax, treated with bilateral transplantation and lung volume reduction with lobectomy.
化脓性肺部疾病,如囊性纤维化和支气管扩张症,当病变弥漫且伴有严重功能丧失时,可通过双侧肺移植进行治疗,效果良好。这些疾病常与既往肺切除术相关,导致胸廓不对称,从而使肺切除困难,并在移植肺与胸腔之间产生比例失调。为治疗这种情况,肺切除术和单肺移植是一种可行的选择;然而,存在相关的合并症且始终需要体外循环。本文描述了2例胸廓不对称的患者,接受了双侧移植和肺叶切除减容术治疗。