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不对称胸廓支气管扩张症的双侧肺移植:一例报告

Bilateral lung transplant for bronchiectasis in asymmetric thorax: a case report.

作者信息

Wang Yeming, Chen Jingyu, Wei Dong, Zheng Mingfeng, Zhang Ji, Wu Bo

机构信息

Wuxi People's Hospital, Department of Thoracic Transplant, Wuxi, China.

出版信息

Exp Clin Transplant. 2011 Dec;9(6):429-31.

Abstract

Patients with suppurative lung diseases such as bronchiectasis and cystic fibrosis can be treated surgically, which leads to an asymmetric thorax, making lung transplant difficult in a volume-reduced hemithorax. We report a 52-year-old man with bronchiectasis and ventilation, dependent on a severe asymmetric thorax, who underwent bilateral lung transplant without cardiopulmonary bypass or extracorporeal membrane oxygenation support. This report suggests that bilateral lung transplant might be an efficient therapeutic option for such patients. Lung transplant is generally accepted as an effective way to deal with end-stage pulmonary diseases. Particularly, in patients with bronchiectasis or cystic fibrosis, single lung transplant may lead to infectious complications more easily. Thus, bilateral lung transplant is a better choice for such patients. However, some patients with bronchiectasis may have a history of surgical resection of target areas, which leads to an asymmetric thorax and makes lung transplant more difficult. We described 1 case of bilateral lung transplant for bronchiectasis in asymmetric thorax.

摘要

患有化脓性肺部疾病(如支气管扩张症和囊性纤维化)的患者可接受手术治疗,这会导致胸廓不对称,使得在患侧肺容积减小的情况下进行肺移植变得困难。我们报告了一名52岁患有支气管扩张症且依赖通气的男性,其胸廓严重不对称,该患者在未进行体外循环或体外膜肺氧合支持的情况下接受了双侧肺移植。本报告表明,双侧肺移植可能是这类患者的一种有效治疗选择。肺移植通常被认为是治疗终末期肺部疾病的有效方法。特别是,对于患有支气管扩张症或囊性纤维化的患者,单肺移植可能更容易导致感染并发症。因此,双侧肺移植是这类患者的更好选择。然而,一些支气管扩张症患者可能有靶区手术切除史,这会导致胸廓不对称并使肺移植更加困难。我们描述了1例针对胸廓不对称的支气管扩张症患者进行双侧肺移植的病例。

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