Nishioka Hiroshi, Shibuya Makoto, Nakajima Satoshi, Ohno Shingo, Ikeda Yukio
Department of Neurosurgery, Hachioji Medical Center, Tokyo Medical University, Tokyo 193-0998, Japan.
Surg Neurol. 2009 Jun;71(6):685-8, discussion 688. doi: 10.1016/j.surneu.2008.01.045. Epub 2008 May 1.
Inflammatory pseudotumor primarily affecting the CNS is an extremely rare lesion with uncertain etiology in most cases.
A 67-year-old man developed involuntary movement disorder of the left upper extremity. On MRI, a solid homogeneously-enhanced tumor was noted in the right lateral ventricle adjacent to the thalamus. He had histories of right thalamic hypertensive hemorrhage and recurrent chronic nasal sinusitis associated with an orbital mass lesion, presumably an IP. Partial removal of the tumor yielded a diagnosis of IP associated with EBV infection.
The simultaneous occurrence of multiple IPs was presumably because of an exaggerated immune process after EBV infection. Inflammatory pseudotumor should be considered in any case of intraventricular mass lesion.
主要累及中枢神经系统的炎性假瘤是一种极为罕见的病变，多数情况下病因不明。
一名67岁男性出现左上肢不自主运动障碍。磁共振成像（MRI）显示，在右侧脑室靠近丘脑处有一个实性均匀强化肿瘤。他有右侧丘脑高血压性出血病史，以及复发性慢性鼻窦炎伴眼眶肿块病变，推测为炎性假瘤（IP）。肿瘤部分切除后诊断为与EB病毒感染相关的炎性假瘤。
多个炎性假瘤同时出现可能是由于EB病毒感染后免疫反应过度。对于任何脑室内肿块病变病例都应考虑炎性假瘤。
