The role of postoperative radiotherapy in carcinoma of the endometrium.

The role of adjuvant postoperative radiotherapy in endometrial carcinoma after surgery remains controversial. There is a great variation between centres in deciding when to give postoperative external beam radiotherapy and/or vaginal vault brachytherapy for patients with endometrial carcinoma. The role of pelvic and para-aortic lymphadenectomy as well as the need for postoperative radiotherapy after this type of surgical staging continue to be debated. Furthermore, the role of adjuvant chemotherapy either alone or in combination with adjuvant radiotherapy also remains to be determined. This overview discusses the role of postoperative radiotherapy in the context of surgery and other adjuvant treatments in carcinoma of the endometrium.