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脂质调节药物在冠心病复杂病程中的应用。

Use of lipid-modulating drugs in complicated course of coronary heart disease.

作者信息

Gratsianskii N A, Vaulin N A

机构信息

Laboratory of Clinical Cardiology, Institute of Physicochemical Medicine, Federal Agency on Health Care and Social Development, Moscow.

出版信息

Bull Exp Biol Med. 2007 Sep;144(3):438-46. doi: 10.1007/s10517-007-0348-8.

DOI:10.1007/s10517-007-0348-8
PMID:18457052
Abstract

We present the results of the study of lipid-modulating drugs (pravastatin, atorvastatin, simvastatin, and fibrate gemfibrozil) in complicated coronary heart disease (acute coronary syndrome without ST elevation, chronic heart failure. In acute coronary syndrome statins produced a positive effect on some studied parameters, while in heart failure only the safety of short-term therapy with statins was demonstrated.

摘要

我们展示了脂质调节药物(普伐他汀、阿托伐他汀、辛伐他汀和贝特类药物吉非贝齐)在复杂性冠心病(非ST段抬高型急性冠脉综合征、慢性心力衰竭)中的研究结果。在急性冠脉综合征中,他汀类药物对一些研究参数产生了积极影响,而在心力衰竭中,仅证明了他汀类药物短期治疗的安全性。

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