Hensel Manfred, Zoz Martin, Ho Anthony D
Department of Medicine V, University of Heidelberg, Heidelberg, Germany.
Support Care Cancer. 2009 Jan;17(1):47-52. doi: 10.1007/s00520-008-0452-y. Epub 2008 May 6.
Despite the widespread use of complementary and alternative medicine (CAM) in the general population for the treatment of chronic diseases, only few data have been published for patients with leukemia. The aim of this survey was to study systematically the use of CAM in patients with chronic lymphocytic leukemia (CLL).
A structured questionnaire was sent to 247 CLL patients of all clinical stages and disease durations, treated and untreated. The questionnaire was returned anonymously by 87 patients (35%).
Thirty-nine patients (44%) had used alternative treatments. No correlation was seen with educational level, gender, or previous or current chemotherapy. The most common alternative or complementary treatment modality was vitamin supplementation (26%), followed by mineral (18%), homeopathic (14%), and mistletoe therapy (9.2%). Some 21% of patients considered their alternative treatment as being successful. Most patients reported that they decided to use CAM after conducting a personal investigation and based on the information they found, without outside recommendations (59%). The majority of the patients used patient brochures about CLL as an important source of information (54%), followed by specific lectures (34%) or the internet (32%).
Our data show that patients with CLL use a wide range of CAM, among them potentially harmful methods. Rational, evidence-based medical information about the effects and risks of CAM use should be made available through patient brochures distributed by patient organizations, through information events with lectures, or via the internet.
尽管补充和替代医学（CAM）在普通人群中广泛用于治疗慢性病，但关于白血病患者使用该疗法的数据却很少。本次调查的目的是系统研究慢性淋巴细胞白血病（CLL）患者对补充和替代医学的使用情况。
向247例处于所有临床分期、病程各异且无论是否接受治疗的CLL患者发放了一份结构化问卷。87例患者（35%）匿名回复了问卷。
39例患者（44%）使用过替代疗法。未发现与教育程度、性别或既往及当前化疗存在相关性。最常见的替代或补充治疗方式是补充维生素（26%），其次是补充矿物质（18%）、顺势疗法（14%）和槲寄生疗法（9.2%）。约21%的患者认为其替代治疗取得了成功。大多数患者报告称，他们是在自行调查并依据所获信息后决定使用补充和替代医学的，而非基于外部建议（59%）。大多数患者将关于CLL的患者宣传册作为重要信息来源（54%），其次是专题讲座（34%）或互联网（32%）。
我们的数据表明，CLL患者使用多种补充和替代医学疗法，其中一些可能有害。应通过患者组织发放的患者宣传册、举办带讲座的信息活动或通过互联网，提供关于补充和替代医学使用效果及风险的合理、基于证据的医学信息。
