Tsikouras P, Liberis V, Galazios G, Savidis A, Grapsa A, Grapsas X, Teichmann A T, Maroulis G
Department of Obstetrics and Gynecology, Democritus University of Thrace, Greece.
Eur J Gynaecol Oncol. 2008;29(2):129-34.
Uterine sarcomas comprese approximately 4-9% of all uterine malignant tumors with a poor prognosis. We report 57 cases of sarcoma originating in the uterus treated from 1990 to 2006 at the Department of Obstetrics and Gynecology of Democritus University of Thrace, Greece and the Department of Obstetrics and Gynecology of Aschaffenburg Hospital, Germany. The median age of occurrence was 49 years with the commonest symptom being abnormal uterine bleeding. Forty-nine patients underwent a total hysterectomy and bilateral salpingo-oophorectomy whereas 17 cases underwent radical lymphadenectomy. During the last followup (December 2006), six patients were alive and well with no evidence of disease, 23 patients had died of undercurrent disease, and 28 were alive with recurrence of disease. These rare cancers can be aggressive, and account for a greatly disproportionate number of deaths from uterine cancers. Treatment for this rare disease should be performed according to international protocols in order to have the most updated information.
子宫肉瘤约占所有子宫恶性肿瘤的4% - 9%，预后较差。我们报告了1990年至2006年期间在希腊色雷斯德谟克利特大学妇产科和德国阿沙芬堡医院妇产科治疗的57例子宫肉瘤病例。发病的中位年龄为49岁，最常见的症状是子宫异常出血。49例患者接受了全子宫切除术和双侧输卵管卵巢切除术，17例患者接受了根治性淋巴结清扫术。在最后一次随访（2006年12月）时，6例患者存活且状况良好，无疾病证据，23例患者死于相关疾病，28例患者存活但疾病复发。这些罕见癌症可能具有侵袭性，在子宫癌死亡病例中占比极大。应根据国际方案对这种罕见疾病进行治疗，以便获取最新信息。
