Yacoub George, Kosseifi Semaan G, Shah Lata S, Byrd Ryland P, Roy Thomas M
Veterans Affairs Medical Center, Mountain Home, TN, USA.
Tenn Med. 2008 Mar;101(3):35-7, 40.
The occurrence of glomerular disease as a paraneoplastic manifestation of malignancy is well documented in the medical literature. The strongest association is between membranous glomerulonephritis and solid tumors. We report a patient with IgA nephropathy associated with small cell lung cancer. To our knowledge, this is the second documented occurrence of an IgA nephropathy with a casual association with small cell bronchogenic cancer. This observation leads to the hypothesis that IgA nephropathy might be a paraneoplastic manifestation of this histiologic type of lung cancer.
肾小球疾病作为恶性肿瘤的副肿瘤表现已在医学文献中得到充分记载。最强的关联是膜性肾小球肾炎与实体瘤之间的关联。我们报告了一例患有与小细胞肺癌相关的IgA肾病的患者。据我们所知,这是第二例记录在案的与小细胞支气管源性癌偶然相关的IgA肾病。这一观察结果引发了一个假说,即IgA肾病可能是这种组织学类型肺癌的副肿瘤表现。