Lee Jae-il, Kim Young-suk, Kim Myung-Jin, Hong Sung-Hyeok
Department of Experimental Animal Research, Clinical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.
J Am Assoc Lab Anim Sci. 2008 May;47(3):68-71.
A 6.5-y-old cynomolgus monkey was referred to the Veterinary Medical Teaching Hospital at Chungnam National University for suspected bone fracture. The monkey had been reared singly in a cage at a laboratory facility. An animal caretaker incidentally found a bone fragment protruding through the skin of the right leg. Radiographic examination revealed 2 new bone fragments clearly distinguishable from the original femurs; the fragments seemed to be inserted into both femurs. One of the new bone fragments was easily separated surgically from the right femur. Although the bone fragment consisted of a medullary cavity and bone cortex, the periosteal structure was incomplete. New bone formation in nonhuman primates, as manifested in this case, has been reported previously. However, growth of an additional long bone from the original, penetrating the skin without motional disturbance, has not been reported previously.
一只6.5岁的食蟹猴因疑似骨折被转诊至忠南国立大学兽医学院教学医院。这只猴子一直单独饲养在实验室设施的笼子里。一名动物饲养员偶然发现一块骨碎片从右腿皮肤穿出。X线检查发现2块新的骨碎片，与原来的股骨明显不同；这些碎片似乎插入了两侧股骨。其中一块新骨碎片很容易通过手术从右股骨上分离出来。虽然这块骨碎片由髓腔和骨皮质组成，但骨膜结构不完整。非人类灵长类动物出现的这种新骨形成情况，此前已有报道。然而，从原来的骨骼上额外长出一根长骨并穿透皮肤且无运动障碍，此前尚未见报道。
