Cho Sukki, Jheon Sanghoon, Ryu Kyung-Min, Lee Eung Bae
Department of Thoracic and Cardiovascular Surgery, Kyungpook National University Hospital, Jung-gu, Daegu, Korea.
Dis Esophagus. 2008;21(7):660-3. doi: 10.1111/j.1442-2050.2008.00833.x. Epub 2008 May 2.
Boerhaave's syndrome is the most severe disease in the esophageal perforation. The purpose of this report is to evaluate the outcome in patients who were treated with primary repair for Boerhaave's syndrome regardless of the time interval. From 1997 to July 2007, 10 patients with Boerhaave's syndrome were treated with primary repair regardless of the time interval. The interval between rupture and initial treatment was less than 24 hours in five patients (50.0%) and more than 24 hours in the other five patients (50.0%). There was no operative mortality and five postoperative leaks. Of these five patients with postoperative leaks, one received primary repair for less than 24 hours (20%) and four received operation for more than 24 hours (80%). However, postoperative leaks were managed by non-operative methods and resolved within 2 weeks. The time interval between perforation and operative intervention should not prejudice the surgeon against primary repair of Boerhaave's syndrome. Although a high incidence of postoperative leak occurred in patients who were operated on for more than 24 hours, its management is not hard to perform and its prognosis was not poor.
博雷哈夫综合征是食管穿孔中最严重的疾病。本报告的目的是评估无论时间间隔如何均接受一期修复治疗的博雷哈夫综合征患者的治疗结果。1997年至2007年7月,10例博雷哈夫综合征患者无论时间间隔如何均接受了一期修复治疗。5例患者(50.0%)破裂至初始治疗的间隔时间小于24小时,另外5例患者(50.0%)则超过24小时。无手术死亡病例,术后有5例发生渗漏。在这5例术后渗漏患者中,1例接受一期修复的时间小于24小时(20%),4例接受手术的时间超过24小时(80%)。然而,术后渗漏通过非手术方法处理,2周内得以解决。穿孔与手术干预之间的时间间隔不应使外科医生对博雷哈夫综合征的一期修复产生偏见。虽然手术时间超过24小时的患者术后渗漏发生率较高,但其处理并不困难,预后也不差。