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用于出院前黄疸评估的视觉筛查与经皮胆红素测定法对比

Visual screening versus transcutaneous bilirubinometry for predischarge jaundice assessment.

作者信息

Kaplan Michael, Shchors Irena, Algur Nurit, Bromiker Ruben, Schimmel Michael S, Hammerman Cathy

机构信息

Department of Neonatology Shaare Zedek Medical Center, Jerusalem, Israel.

出版信息

Acta Paediatr. 2008 Jun;97(6):759-63. doi: 10.1111/j.1651-2227.2008.00807.x.

Abstract

OBJECTIVE

Comparison of visual screening with transcutaneous bilirubinometry (TcB) in identifying neonates with plasma total bilirubin (PTB) > or =75th percentile.

DESIGN

In 100 paired readings PTB was 34 +/- 24 micromol/L higher than the TcB counterpart. A TcB reading of 154 micromol/L was therefore regarded as equivalent to a PTB of 188 micromol/L, corresponding to the 75th percentile at 48 h. Predischarge, all newborns were evaluated for jaundice, first by visual inspection and then transcutaneously. PTB was ordered as indicated by visual assessment or if the TcB reading was > or =154 micromol/L.

RESULTS

Of 346 newborns tested, 25 (7.2%) had a PTB concentration > or =75th percentile. Forty-nine had PTB determinations based on TcB compared with 83 by visual assessment. However, a similar number of affected newborns was identified by each method (21/25 (84%) by visual screening vs. 18/25 (72%) by TcB). PTB concentrations of those who had been chosen by TcB were higher than those selected visually (202 +/- 24 micromol/L vs. 186 +/- 31 micromol/L).

CONCLUSIONS

A practical method for predischarge detection of neonates with plasma total bilirubin concentration > or = 75th percentile, implementing transcutaneous bilirubinometry, is described. The transcutaneous technique required fewer blood tests than visual assessment for similar yield.

摘要

目的

比较经皮胆红素测定(TcB)与目视筛查在识别血浆总胆红素(PTB)≥第75百分位数新生儿方面的效果。

设计

在100次配对读数中,PTB比对应的TcB读数高34±24微摩尔/升。因此,TcB读数154微摩尔/升被视为等同于PTB 188微摩尔/升,对应于48小时时的第75百分位数。出院前,对所有新生儿进行黄疸评估,首先通过目视检查,然后经皮测量。根据目视评估结果或TcB读数≥154微摩尔/升时进行PTB检测。

结果

在346名接受检测的新生儿中,25名(7.2%)PTB浓度≥第75百分位数。基于TcB进行PTB测定的有49例,通过目视评估的有83例。然而,两种方法识别出的受影响新生儿数量相似(目视筛查识别出21/25例(84%),TcB识别出18/25例(72%))。通过TcB选择的新生儿的PTB浓度高于通过目视选择的新生儿(分别为202±24微摩尔/升和186±31微摩尔/升)。

结论

描述了一种在出院前检测血浆总胆红素浓度≥第75百分位数新生儿的实用方法,采用经皮胆红素测定法。对于相似的检出率,经皮技术所需的血液检测比目视评估少。

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